{"id":"W2099357929","doi":"10.1073/pnas.1007081107","title":"Single-molecule denaturation mapping of DNA in nanofluidic channels","year":2010,"lang":"en","type":"article","venue":"Proceedings of the National Academy of Sciences","topic":"Nanopore and Nanochannel Transport Studies","field":"Engineering","cited_by":202,"is_retracted":false,"has_abstract":true,"ca_institutions":"McGill University","funders":"","keywords":"Barcode; Denaturation (fissile materials); Sequence (biology); DNA; Molecule; Biological system; Biophysics; Chemistry; Nanotechnology; Computational biology; Chemical physics; Materials science; Biology; Computer science; Biochemistry","routes":{"ca_aff":true,"ca_fund":false,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"codex-gemma-dda1882f352a","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0005369835,0.00007612197,0.0001423341,0.000247421,0.00005729516,0.000006172016,0.0003394588,0.00007687998,0.000004546772],"category_scores_gemma":[0.0001150384,0.0000560742,0.00004827467,0.0008285641,0.0002991836,0.0002751035,0.00003032471,0.0001417952,3.038859e-7],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.00001234223,"about_ca_system_score_gemma":0.000009378155,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.00000296449,"about_ca_topic_score_gemma":3.767346e-7,"domain_scores_codex":[0.9989393,0.000001320982,0.0003133762,0.0001131755,0.0005131965,0.0001196031],"domain_scores_gemma":[0.9996632,0.0000410645,0.0001359757,0.000005544927,0.0001398708,0.00001430584],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","study_design_scores_codex":[0.000002346645,0.00001760151,0.001834383,0.00008523414,0.000007153321,4.723178e-9,0.0003767151,0.0001597793,0.9929349,0.004356125,0.00009246654,0.0001332369],"study_design_scores_gemma":[0.00009806815,0.00001565466,0.01327789,0.00009737991,0.000003711875,0.000001699301,0.000109415,0.0008325928,0.9785001,0.006913281,0.00009042041,0.00005980498],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9962808,0.0002587287,0.000003972318,0.0003770275,0.00007469145,0.0001061809,0.000004524235,0.00001396691,0.002880109],"genre_scores_gemma":[0.9993589,0.00005172054,0.0004896228,0.00002370509,0.00004656224,0.000005933021,1.127966e-7,0.000004005269,0.00001947134],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.01443487,"threshold_uncertainty_score":0.2286639,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.02891705718208339,"score_gpt":0.2485555218206278,"score_spread":0.2196384646385444,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}