{"id":"W2099502558","doi":"10.1002/ana.22024","title":"Gentamicin‐induced readthrough of stop codons in duchenne muscular dystrophy","year":2010,"lang":"en","type":"article","venue":"Annals of Neurology","topic":"Muscle Physiology and Disorders","field":"Biochemistry, Genetics and Molecular Biology","cited_by":272,"is_retracted":false,"has_abstract":true,"ca_institutions":"SickKids Foundation; Hospital for Sick Children; University of Toronto","funders":"National Center for Research Resources; National Institute of Neurological Disorders and Stroke","keywords":"Duchenne muscular dystrophy; Frameshift mutation; Dystrophin; Cohort; Medicine; Stop codon; Gentamicin; Internal medicine; Creatine kinase; Biology; Mutation; Genetics; Gene; Antibiotics","routes":{"ca_aff":true,"ca_fund":false,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"codex-gemma-dda1882f352a","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.000143621,0.0001233778,0.0002501482,0.00007308946,0.00002022191,0.000001159006,0.0002204537,0.0002847447,0.00003759595],"category_scores_gemma":[0.0001445846,0.0001242708,0.0001109896,0.00009229657,0.0002281911,0.000003682659,0.00009082905,0.0002251359,0.000003509047],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":3.758156e-7,"about_ca_system_score_gemma":0.00004185998,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.0001773271,"about_ca_topic_score_gemma":0.0002023823,"domain_scores_codex":[0.9990035,0.0001123395,0.0002816113,0.0002991057,0.0000580052,0.0002453986],"domain_scores_gemma":[0.9992702,0.00002690166,0.0001386964,0.000427884,0.00009251844,0.00004380195],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","study_design_scores_codex":[0.0004197943,0.0001751663,0.004951474,0.00001661655,0.00003130639,0.000005949672,0.0000387781,0.00004856774,0.9926414,0.0006498649,0.000423566,0.0005975019],"study_design_scores_gemma":[0.001092503,0.002425429,0.2092943,0.000004139198,0.00001487973,0.00001824755,0.00003161329,0.00003336205,0.7762275,0.001497814,0.009162844,0.0001973706],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9978742,0.0001121986,0.00001750388,0.00109774,0.0002083877,0.0001127465,0.00001439446,0.000004426143,0.0005584273],"genre_scores_gemma":[0.9981576,0.0001582104,0.00005523342,0.001491174,0.00006291246,0.000007797397,0.00003780926,0.00001349867,0.00001578688],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.2164139,"threshold_uncertainty_score":0.5067617,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.02798341794287475,"score_gpt":0.3057317184188282,"score_spread":0.2777483004759535,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}