{"id":"W2099536314","doi":"10.1007/s10096-005-0024-8","title":"International, open-label, noncomparative, clinical trial of micafungin alone and in combination for treatment of newly diagnosed and refractory candidemia","year":2005,"lang":"en","type":"article","venue":"European Journal of Clinical Microbiology & Infectious Diseases","topic":"Antifungal resistance and susceptibility","field":"Medicine","cited_by":189,"is_retracted":false,"has_abstract":false,"ca_institutions":"Princess Margaret Cancer Centre","funders":"","keywords":"Micafungin; Echinocandin; Refractory (planetary science); Medicine; Candida glabrata; Internal medicine; Adverse effect; Candida albicans; Echinocandins; Candida tropicalis; Gastroenterology; Caspofungin; Amphotericin B; Antifungal; Microbiology; Biology; Dermatology","routes":{"ca_aff":true,"ca_fund":false,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"metacan-v3-hybrid-931329e0061c","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.004334582,0.002956853,0.006616894,0.001159368,0.001030676,0.002265593,0.002569839,0.00360754,0.006269359],"category_scores_gemma":[0.003154883,0.001173875,0.002391577,0.001109918,0.003359328,0.003364494,0.0008019041,0.006764899,0.001274888],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.001441678,"about_ca_system_score_gemma":0.001996001,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.001132276,"about_ca_topic_score_gemma":0.002153393,"domain_scores_codex":[0.9978454,0.00122938,0.0001035574,0.0003236066,0.0001131297,0.0003849163],"domain_scores_gemma":[0.9980447,0.0005078713,0.0002859177,0.0002488333,0.0001019871,0.0008106871],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"randomized_trial","study_design_gemma":"nonrandomized_trial","study_design_scores_codex":[0.961592,0.01788936,0.0003619654,0.0002079512,0.0004338934,0.000046598,0.00006647482,0.0003336584,0.003645498,0.0001211043,0.0006408628,0.01466072],"study_design_scores_gemma":[0.8510028,0.1450069,0.001765106,0.00002068948,0.0002500263,0.00008564608,0.0000297581,0.0004965663,0.0006332615,0.0001103415,0.0005700444,0.00002888438],"study_design_candidate":"nonrandomized_trial","study_design_consensus":null,"genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.985502,0.004546022,0.001146403,0.001086282,0.0006964427,0.002148745,0.001407818,0.000209914,0.003256309],"genre_scores_gemma":[0.9867184,0.002706795,0.002495025,0.0009615431,0.0008825071,0.002111539,0.001833588,0.00004504765,0.00224552],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.006616894,"threshold_uncertainty_score":0.02292377,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.09322631934528273,"score_gpt":0.4379501433405737,"score_spread":0.344723823995291,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}