{"id":"W2099577485","doi":"10.1016/j.ajpath.2011.01.013","title":"Interleukin-1β Inhibition Prevents Choroidal Neovascularization and Does Not Exacerbate Photoreceptor Degeneration","year":2011,"lang":"en","type":"article","venue":"American Journal Of Pathology","topic":"Retinal Diseases and Treatments","field":"Medicine","cited_by":134,"is_retracted":false,"has_abstract":false,"ca_institutions":"McGill University; Centre Hospitalier Universitaire Sainte-Justine","funders":"Institut National de la Santé et de la Recherche Médicale; Agence Nationale de la Recherche","keywords":"Choroidal neovascularization; Macular degeneration; Retinal degeneration; Angiogenesis; CX3CR1; Biology; Endocrinology; Receptor antagonist; Vascular endothelial growth factor; Retina; Internal medicine; Medicine; Antagonist; Receptor; Cancer research; Ophthalmology; Chemokine; Neuroscience; Chemokine receptor","routes":{"ca_aff":true,"ca_fund":false,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"metacan-v3-hybrid-931329e0061c","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0003005975,0.0007981319,0.001022243,0.0005812839,0.0003447322,0.0005328587,0.0005472975,0.0008847719,0.003178603],"category_scores_gemma":[0.0004159812,0.0002873035,0.000620621,0.0002351699,0.0007766308,0.0006555357,0.0002431832,0.002563785,0.0007493868],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.0003607379,"about_ca_system_score_gemma":0.0007841139,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.0009423488,"about_ca_topic_score_gemma":0.001509643,"domain_scores_codex":[0.9995183,0.000078349,0.0000550842,0.00006545742,0.00008672377,0.0001961356],"domain_scores_gemma":[0.999288,0.0001000547,0.0001675632,0.00009332161,0.00004620684,0.0003047558],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","study_design_scores_codex":[0.01056745,0.002578293,0.0008942134,0.000330005,0.00009322033,0.0005181992,0.00008001796,0.0002819629,0.9712129,0.0005375785,0.001656943,0.01124914],"study_design_scores_gemma":[0.002500269,0.01422632,0.01720806,0.00007005148,0.0001891726,0.001541531,0.0002489763,0.001676012,0.9542597,0.000557052,0.007473975,0.00004891883],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9920818,0.002679071,0.001103952,0.0006152656,0.0003075702,0.0000657976,0.0005469291,0.000278883,0.002320722],"genre_scores_gemma":[0.9934738,0.001231269,0.00123961,0.0002346349,0.0001120567,0.000131618,0.0007975895,0.00004471518,0.002734623],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.003178603,"threshold_uncertainty_score":0.01063347,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.01305311203654588,"score_gpt":0.2496473533188449,"score_spread":0.236594241282299,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}