{"id":"W2099656577","doi":"10.2337/db12-0259","title":"Inhibition of Carnitine Palmitoyltransferase-1 Activity Alleviates Insulin Resistance in Diet-Induced Obese Mice","year":2012,"lang":"en","type":"article","venue":"Diabetes","topic":"Adipose Tissue and Metabolism","field":"Medicine","cited_by":127,"is_retracted":false,"has_abstract":true,"ca_institutions":"University of Alberta","funders":"Alberta Heritage Foundation for Medical Research; University of Alberta","keywords":"Internal medicine; Endocrinology; Insulin resistance; GLUT4; Skeletal muscle; Insulin; Glucose uptake; Beta oxidation; Insulin receptor; Carnitine; Fatty acid; Biology; Chemistry; Metabolism; Medicine; Biochemistry","routes":{"ca_aff":true,"ca_fund":true,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"codex-gemma-dda1882f352a","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0002882752,0.0001533872,0.0004177674,0.00012573,0.00002788315,0.000004036809,0.00004274868,0.0001117452,0.00005803259],"category_scores_gemma":[0.0002043128,0.0001401057,0.00007407001,0.0002572455,0.00004810312,0.0002054626,0.00001681173,0.0002052393,0.00002313486],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.00002926722,"about_ca_system_score_gemma":0.00003498316,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.00006867912,"about_ca_topic_score_gemma":0.0000644738,"domain_scores_codex":[0.9989189,0.00008442926,0.0002544023,0.000169447,0.0001908317,0.0003819717],"domain_scores_gemma":[0.9993997,0.0001180227,0.0000738563,0.0002005104,0.00007404741,0.0001338529],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","study_design_scores_codex":[0.0001839138,0.0004344432,0.1081377,0.0002840096,0.00003932921,0.000005289013,0.001232787,1.454541e-7,0.8860368,0.0001752576,0.00007944503,0.003390861],"study_design_scores_gemma":[0.001093427,0.00009628679,0.345481,0.0002449775,0.00006937751,3.761768e-7,0.00006892625,0.000003359559,0.6515009,0.00008626873,0.001244257,0.0001107519],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9888888,0.008445793,0.000004613241,0.0003238316,0.0001370092,0.0002967456,0.00002291837,0.00003494647,0.001845316],"genre_scores_gemma":[0.9988363,0.000264594,0.0002356421,0.0001451226,0.0002483577,0.00003423916,0.0000387915,0.00002344953,0.0001735409],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.2373434,"threshold_uncertainty_score":0.5713345,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.02034712962163317,"score_gpt":0.2633988755396197,"score_spread":0.2430517459179865,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}