{"id":"W2099782488","doi":"10.1016/j.chom.2012.01.005","title":"Subversion of Autophagy by Kaposi's Sarcoma-Associated Herpesvirus Impairs Oncogene-Induced Senescence","year":2012,"lang":"en","type":"article","venue":"Cell Host & Microbe","topic":"Cytomegalovirus and herpesvirus research","field":"Medicine","cited_by":111,"is_retracted":false,"has_abstract":false,"ca_institutions":"Beatrice Hunter Cancer Research Institute; Dalhousie University","funders":"Canadian Institutes of Health Research; Shanghai Ocean University; Canadian Cancer Society","keywords":"Biology; Autophagy; Senescence; Cyclin; Cell cycle; Cell biology; Cell cycle checkpoint; Viral Oncogene; Oncogene; Kaposi's sarcoma-associated herpesvirus; DNA damage; Cancer research; Cell; Virology; Gene; Genetics; DNA; Virus; Apoptosis; Herpesviridae","routes":{"ca_aff":true,"ca_fund":true,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"codex-gemma-dda1882f352a","candidate_categories":["metaepi_narrow","insufficient_payload"],"consensus_categories":[],"category_scores_codex":[0.0006182697,0.000335969,0.0006417164,0.0002097183,0.0001692076,0.0000268377,0.0002860072,0.0003546992,0.0009610327],"category_scores_gemma":[0.000069992,0.0003116517,0.0002860169,0.0005874317,0.000140705,0.0001962045,0.0002064136,0.0004962294,0.000553006],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.0004283363,"about_ca_system_score_gemma":0.0002784454,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.00131326,"about_ca_topic_score_gemma":0.00004118371,"domain_scores_codex":[0.997371,0.000143228,0.0005176677,0.0004115738,0.0005390659,0.001017501],"domain_scores_gemma":[0.9982911,0.0001182957,0.0002275105,0.000567332,0.0002400353,0.0005557151],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","study_design_scores_codex":[0.0003010708,0.001284616,0.01788076,0.0001504784,0.00007829162,0.00002715972,0.0005707885,2.425765e-7,0.9622179,0.000007430333,0.0144532,0.003028108],"study_design_scores_gemma":[0.002723536,0.0003909294,0.01300453,0.0001107751,0.0001080618,0.00002963484,0.0001852232,0.00003310514,0.943479,0.000002394027,0.03964254,0.0002902782],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9889618,0.005613069,0.00002426927,0.0002471692,0.0002349056,0.0005659363,0.000107081,0.00009425486,0.004151574],"genre_scores_gemma":[0.9946805,0.0004363375,0.0001706388,0.0003750447,0.0001462646,0.00001143665,0.0001063348,0.00007453269,0.003998959],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.02518934,"threshold_uncertainty_score":0.9999522,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.02008714625233386,"score_gpt":0.2886025941581784,"score_spread":0.2685154479058445,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}