{"id":"W2099854994","doi":"10.4049/jimmunol.1003081","title":"Cutting Edge: TIGIT Has T Cell-Intrinsic Inhibitory Functions","year":2011,"lang":"en","type":"article","venue":"The Journal of Immunology","topic":"Immune Cell Function and Interaction","field":"Immunology and Microbiology","cited_by":569,"is_retracted":false,"has_abstract":true,"ca_institutions":"Juvenile Diabetes Research Foundation","funders":"National Institute of Neurological Disorders and Stroke; National Institute of Allergy and Infectious Diseases; Wellcome Trust","keywords":"TIGIT; T cell; Autoimmunity; CD80; Cell biology; Immunology; CD28; Biology; Cancer research; Immune system; Cytotoxic T cell; In vitro; CD40; Genetics","routes":{"ca_aff":true,"ca_fund":false,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"metacan-v3-hybrid-931329e0061c","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0002740468,0.0005881024,0.0005469666,0.0002182148,0.000334838,0.001404949,0.0004968839,0.001044797,0.004595207],"category_scores_gemma":[0.0002797497,0.0001606801,0.0004205263,0.0003722743,0.0005066826,0.0005815479,0.0003610295,0.001458476,0.002147038],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.0004999764,"about_ca_system_score_gemma":0.0003364448,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.0001572105,"about_ca_topic_score_gemma":0.0002205407,"domain_scores_codex":[0.9997575,0.00002285057,0.00001307529,0.00006850895,0.00008352273,0.00005445953],"domain_scores_gemma":[0.9997774,0.00004010308,0.00005774866,0.00002687566,0.00003248688,0.00006531081],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","study_design_scores_codex":[0.0003978918,0.00005524072,0.001623951,0.000454776,0.00003727515,0.0002019633,0.00002801285,0.0001855235,0.954325,0.001941555,0.001996875,0.03875183],"study_design_scores_gemma":[0.00006581952,0.0008784544,0.01637739,0.0001205705,0.000192456,0.002749036,0.00009948493,0.0016126,0.8934919,0.002087831,0.08229552,0.00002903106],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.8297487,0.1195629,0.01626213,0.007020079,0.001553346,0.00007333568,0.001379239,0.000618438,0.02378179],"genre_scores_gemma":[0.958846,0.01976256,0.006230528,0.002575677,0.0006695186,0.00003388032,0.00145351,0.00007890011,0.01034952],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.004595207,"threshold_uncertainty_score":0.01537251,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.02581069071281808,"score_gpt":0.2115990943713296,"score_spread":0.1857884036585115,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}