{"id":"W2099862791","doi":"10.2337/dc13-0626","title":"B-Lymphocyte Depletion With Rituximab and β-Cell Function: Two-Year Results","year":2013,"lang":"en","type":"article","venue":"Diabetes Care","topic":"Diabetes and associated disorders","field":"Biochemistry, Genetics and Molecular Biology","cited_by":282,"is_retracted":false,"has_abstract":true,"ca_institutions":"SickKids Foundation; Hospital for Sick Children; University of Toronto","funders":"National Center for Advancing Translational Sciences; National Center for Research Resources; U.S. National Library of Medicine; Genentech; MacroGenics; Novo Nordisk; Dexcom; MannKind Corporation; Biogen; Osiris Therapeutics; GlaxoSmithKline; Eli Lilly and Company; AstraZeneca; Amylin Pharmaceuticals; Juvenile Diabetes Research Foundation International; National Institute of Diabetes and Digestive and Kidney Diseases; Amgen; Pfizer; Halozyme; Sanofi; American Diabetes Association","keywords":"Rituximab; Medicine; Placebo; Internal medicine; Gastroenterology; Area under the curve; Diabetes mellitus; Immunology; Endocrinology; Lymphoma; Pathology","routes":{"ca_aff":true,"ca_fund":false,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"codex-gemma-dda1882f352a","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.00004119341,0.0001415709,0.0001182466,0.00002483651,0.00008410474,0.00006398904,0.00006925534,0.00009528588,0.00002091186],"category_scores_gemma":[0.00001822629,0.0001222485,0.000041624,0.00006985221,0.0000520976,0.000008629036,0.00004990504,0.00005300543,0.0001051392],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.0000141577,"about_ca_system_score_gemma":0.00002943596,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.00002551765,"about_ca_topic_score_gemma":0.00002536436,"domain_scores_codex":[0.9991891,0.00002680186,0.0001111578,0.0003102803,0.0001004417,0.0002622229],"domain_scores_gemma":[0.999512,0.0000084576,0.0000608291,0.0002038231,0.0001364321,0.0000785142],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"observational","study_design_gemma":"bench_or_experimental","study_design_scores_codex":[0.0002998381,0.000286053,0.7314819,0.0002150314,0.000273588,0.000002324457,0.0004011228,0.0001305336,0.1983316,0.00008946077,0.0251515,0.0433371],"study_design_scores_gemma":[0.05562516,0.006095269,0.2695517,0.0002310118,0.0004510828,0.000003081085,0.01709526,0.0004095715,0.3672967,0.0003962109,0.28002,0.002825],"study_design_candidate":"observational","study_design_consensus":null,"genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9889528,0.0018358,0.000009698695,0.000089929,0.00007139842,0.0001816143,0.00006146078,0.00002473197,0.008772606],"genre_scores_gemma":[0.9983174,0.00008990432,0.0001804563,0.0004112672,0.00009599837,0.00004531938,0.0005707853,0.00002385124,0.0002650382],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.4619302,"threshold_uncertainty_score":0.498515,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.002606189588074615,"score_gpt":0.1753319506538577,"score_spread":0.1727257610657831,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}