{"id":"W2099863580","doi":"10.1093/jat/30.1.1","title":"Evidence of Morphine Metabolism to Hydromorphone in Pain Patients Chronically Treated with Morphine","year":2006,"lang":"en","type":"article","venue":"Journal of Analytical Toxicology","topic":"Pain Mechanisms and Treatments","field":"Medicine","cited_by":81,"is_retracted":false,"has_abstract":true,"ca_institutions":"Centre for Addiction and Mental Health; Mount Sinai Hospital","funders":"","keywords":"Hydromorphone; Morphine; Anesthesia; Medicine; Pharmacology; Opioid; Internal medicine; Receptor","routes":{"ca_aff":true,"ca_fund":false,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"metacan-v3-hybrid-931329e0061c","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0002494001,0.0002216375,0.0004013781,0.0006586648,0.0004864246,0.0005946281,0.0002012134,0.000362309,0.001433829],"category_scores_gemma":[0.001821486,0.0002628097,0.0002750131,0.000497409,0.0004392984,0.0002722252,0.0003316386,0.0003859304,0.0001775855],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.0002169479,"about_ca_system_score_gemma":0.00031439,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.001286674,"about_ca_topic_score_gemma":0.00204727,"domain_scores_codex":[0.9996043,0.0001091538,0.00006047464,0.00005824592,0.0001033803,0.00006453898],"domain_scores_gemma":[0.9983246,0.0004138737,0.0007133434,0.00009985148,0.0001800753,0.0002683291],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"observational","study_design_gemma":"observational","study_design_scores_codex":[0.001044929,0.0000907873,0.9783309,0.00004941219,0.00006538453,0.002284874,0.0003884913,0.00003195607,0.0137506,0.00002256455,0.00004259349,0.003897531],"study_design_scores_gemma":[0.00002754624,0.001164706,0.9904784,0.00001125781,0.00005081526,0.00594563,0.0002327301,0.0001369223,0.001706167,0.00001616267,0.0002231379,0.000006515926],"study_design_candidate":"observational","study_design_consensus":"observational","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9992369,0.0003588872,0.00006553792,0.00001627395,0.000003147512,0.000006126177,0.00003524867,0.000002119603,0.0002757269],"genre_scores_gemma":[0.9996344,0.0001348469,0.00007100199,0.00003060887,0.000006964984,0.000004340743,0.00005792693,0.000001247756,0.00005878743],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.001433829,"threshold_uncertainty_score":0.004796624,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.02189304590426716,"score_gpt":0.2809887010058398,"score_spread":0.2590956551015726,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}