{"id":"W2099871879","doi":"10.3109/10409238.2011.636505","title":"Proteins that bind and move lipids: MsbA and NPC1","year":2011,"lang":"en","type":"review","venue":"Critical Reviews in Biochemistry and Molecular Biology","topic":"Lysosomal Storage Disorders Research","field":"Medicine","cited_by":27,"is_retracted":false,"has_abstract":true,"ca_institutions":"University of Guelph","funders":"","keywords":"NPC1; Flippase; Biochemistry; Endosome; Membrane protein; Integral membrane protein; Inner membrane; Biology; Bacterial outer membrane; Cell biology; Peripheral membrane protein; Lipid bilayer; Transport protein; Plant lipid transfer proteins; Membrane lipids; Chemistry; Membrane; Intracellular; Phospholipid; Escherichia coli","routes":{"ca_aff":true,"ca_fund":false,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"metacan-v3-hybrid-931329e0061c","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0001684453,0.0007667928,0.0006636439,0.0004402192,0.0003828703,0.001156921,0.0003994,0.001041535,0.001806444],"category_scores_gemma":[0.0002411321,0.0002266973,0.0003201243,0.0005383758,0.0003465675,0.001385235,0.0004142328,0.000856955,0.001893331],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.001125351,"about_ca_system_score_gemma":0.0009390913,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.001255012,"about_ca_topic_score_gemma":0.001012443,"domain_scores_codex":[0.9998707,0.00001326415,0.00001233211,0.00003198104,0.00004512566,0.00002662904],"domain_scores_gemma":[0.999931,0.000009583277,0.00001698647,0.000002611954,0.00002452774,0.00001524191],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"design_other","study_design_gemma":"not_applicable","study_design_scores_codex":[0.0006861453,0.00007575055,0.001688706,0.01746753,0.0001906637,0.002256822,0.0006761132,0.002287821,0.4352993,0.02529299,0.03154993,0.4825282],"study_design_scores_gemma":[0.00001159558,0.00009846071,0.001470564,0.0002887121,0.00006313751,0.002715916,0.0001252169,0.0003416767,0.05020767,0.001401253,0.9432473,0.00002839205],"study_design_candidate":"not_applicable","study_design_consensus":null,"genre_codex":"review","genre_gemma":"review","genre_scores_codex":[0.02248612,0.9521458,0.006626449,0.001764638,0.001075614,0.00007184376,0.0004902462,0.000262539,0.01507674],"genre_scores_gemma":[0.08870234,0.8694551,0.006253145,0.001385658,0.0005107288,0.0001253694,0.001673382,0.00005897429,0.03183523],"genre_candidate":"review","genre_consensus":"review","teacher_disagreement_score":0.001806444,"threshold_uncertainty_score":0.008165002,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.07344059247853084,"score_gpt":0.414039406080859,"score_spread":0.3405988136023281,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}