{"id":"W2099874384","doi":"10.1152/ajpgi.90690.2008","title":"Hepatocyte nuclear factor 4α contributes to an intestinal epithelial phenotype in vitro and plays a partial role in mouse intestinal epithelium differentiation","year":2009,"lang":"en","type":"article","venue":"American Journal of Physiology-Gastrointestinal and Liver Physiology","topic":"Pancreatic function and diabetes","field":"Medicine","cited_by":94,"is_retracted":false,"has_abstract":true,"ca_institutions":"Université de Sherbrooke","funders":"University of Michigan","keywords":"Intestinal epithelium; Biology; Hepatocyte nuclear factors; Cell biology; Epithelium; Transcription factor; Hepatocyte nuclear factor 4; Hepatocyte; FOXA2; Homeostasis; Intestinal mucosa; Cholangiocyte; Phenotype; Hepatocyte growth factor; Enteroendocrine cell; Immunology; Endocrinology; Internal medicine; In vitro; Genetics; Endocrine system; Gene; Nuclear receptor; Medicine","routes":{"ca_aff":true,"ca_fund":false,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"metacan-v3-hybrid-931329e0061c","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0002244682,0.000524918,0.0002668951,0.0006165395,0.0002210209,0.0004129485,0.0002405557,0.0002527189,0.001438737],"category_scores_gemma":[0.0001158807,0.0003756847,0.0004720229,0.0002208423,0.0002619257,0.0002112447,0.000352531,0.0008070074,0.0013556],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.0004100255,"about_ca_system_score_gemma":0.0002735985,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.001203785,"about_ca_topic_score_gemma":0.001651051,"domain_scores_codex":[0.9997756,0.00004199138,0.00002587828,0.00003258872,0.00006831791,0.00005569918],"domain_scores_gemma":[0.9997719,0.00002398317,0.0000389191,0.00005329193,0.00002623472,0.00008568546],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","study_design_scores_codex":[0.0000944844,0.00001409786,0.000121554,0.00002206612,0.000002209232,0.00003929882,0.000009339364,0.00002791151,0.9989647,0.00005013365,0.00001534556,0.0006388411],"study_design_scores_gemma":[0.00001389808,0.0001759495,0.003780116,0.000007786978,0.00001691563,0.0002143127,0.00003303618,0.0003342005,0.9919058,0.00004276801,0.003472172,0.000003019295],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9777374,0.007824292,0.006859989,0.0001897493,0.00006888096,0.00006205086,0.001181663,0.0002579867,0.005817932],"genre_scores_gemma":[0.9708819,0.004459213,0.003719579,0.00009198402,0.00002013832,0.00007088506,0.00285843,0.00009456782,0.01780334],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.001438737,"threshold_uncertainty_score":0.004813075,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.008488158406706504,"score_gpt":0.2298749253569715,"score_spread":0.221386766950265,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}