{"id":"W2099874384","doi":"10.1152/ajpgi.90690.2008","title":"Hepatocyte nuclear factor 4α contributes to an intestinal epithelial phenotype in vitro and plays a partial role in mouse intestinal epithelium differentiation","year":2009,"lang":"en","type":"article","venue":"American Journal of Physiology-Gastrointestinal and Liver Physiology","topic":"Pancreatic function and diabetes","field":"Medicine","cited_by":94,"is_retracted":false,"has_abstract":true,"ca_institutions":"Université de Sherbrooke","funders":"University of Michigan","keywords":"Intestinal epithelium; Biology; Hepatocyte nuclear factors; Cell biology; Epithelium; Transcription factor; Hepatocyte nuclear factor 4; Hepatocyte; FOXA2; Homeostasis; Intestinal mucosa; Cholangiocyte; Phenotype; Hepatocyte growth factor; Enteroendocrine cell; Immunology; Endocrinology; Internal medicine; In vitro; Genetics; Endocrine system; Gene; Nuclear receptor; Medicine","routes":{"ca_aff":true,"ca_fund":false,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"codex-gemma-dda1882f352a","candidate_categories":["metaepi_narrow"],"consensus_categories":[],"category_scores_codex":[0.0001996502,0.0003243056,0.001039435,0.0004208165,0.00006493492,0.00002026687,0.000140573,0.00005526214,0.00004286448],"category_scores_gemma":[0.0005407882,0.00026083,0.0000949055,0.0002755454,0.0004621604,0.0001752546,0.00006919944,0.0005742582,0.000008202202],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.0000859811,"about_ca_system_score_gemma":0.00009734869,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.0002375829,"about_ca_topic_score_gemma":0.000009558273,"domain_scores_codex":[0.9979701,0.0003112092,0.0006532569,0.000423384,0.0001370439,0.0005049909],"domain_scores_gemma":[0.9985214,0.0003383584,0.0004164995,0.0001668911,0.0002076049,0.0003492352],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"bench_or_experimental","study_design_gemma":"observational","study_design_scores_codex":[0.008932075,0.0005265081,0.02338095,0.00002076986,0.00002903489,0.00003535442,0.0004161477,0.0000363415,0.9559649,0.0001679656,0.000009748382,0.01048021],"study_design_scores_gemma":[0.003026041,0.01320307,0.948571,0.000288816,0.00006440734,0.0007613167,0.0006809846,0.005105544,0.02691657,0.001125274,0.00002708151,0.0002298834],"study_design_candidate":"bench_or_experimental","study_design_consensus":null,"genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9988112,0.000100403,0.0002328292,0.0005246103,0.00005194037,0.000219036,0.00001807926,0.0000251001,0.00001677004],"genre_scores_gemma":[0.9935701,0.00003644267,0.004991854,0.001101633,0.0002511744,0.000005854889,0.00001651587,0.00001907146,0.000007316835],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.9290484,"threshold_uncertainty_score":0.9999844,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.008488158406706504,"score_gpt":0.2298749253569715,"score_spread":0.221386766950265,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}