{"id":"W2099925167","doi":"10.1128/iai.01581-06","title":"<i>Burkholderia cenocepacia</i> Requires a Periplasmic HtrA Protease for Growth under Thermal and Osmotic Stress and for Survival In Vivo","year":2007,"lang":"en","type":"article","venue":"Infection and Immunity","topic":"Vibrio bacteria research studies","field":"Biochemistry, Genetics and Molecular Biology","cited_by":76,"is_retracted":false,"has_abstract":true,"ca_institutions":"Western University; University of Calgary","funders":"Department of Education of Guangdong Province","keywords":"Biology; Periplasmic space; Operon; Burkholderia cenocepacia; Complementation; Microbiology; Virulence; Proteases; Molecular biology; Gene; Mutant; Genetics; Escherichia coli; Biochemistry","routes":{"ca_aff":true,"ca_fund":false,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"metacan-v3-hybrid-931329e0061c","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0001272698,0.0003110025,0.0002098281,0.00009462219,0.0001031937,0.0003758958,0.0001599982,0.0001675016,0.0005287356],"category_scores_gemma":[0.0002085541,0.00009168483,0.000132398,0.0001256539,0.0001736759,0.0001642504,0.0002585876,0.0002949695,0.000466331],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.0002216217,"about_ca_system_score_gemma":0.0002020691,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.001450163,"about_ca_topic_score_gemma":0.001428908,"domain_scores_codex":[0.9998299,0.00002860187,0.00001398863,0.00002589573,0.00006514988,0.00003645273],"domain_scores_gemma":[0.9997788,0.00003147774,0.00008203549,0.00003906134,0.00003073958,0.00003795759],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","study_design_scores_codex":[0.00003365902,0.000009236137,0.0004038036,0.000009906084,0.000001320364,0.00002705634,0.000005923514,0.00001773278,0.9987538,0.00002939563,0.00001988413,0.0006883064],"study_design_scores_gemma":[0.000009389311,0.0001681457,0.02055752,0.000007254294,0.000009501811,0.0006857858,0.00004870351,0.0007000994,0.9754412,0.00005941567,0.002307327,0.000005654706],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9944679,0.0006774825,0.003398707,0.0001399063,0.00001200948,0.00001388796,0.0003792116,0.00009653374,0.0008143797],"genre_scores_gemma":[0.9945682,0.000262019,0.002813939,0.00005833024,0.000007254488,0.00001558252,0.001041099,0.0000233812,0.001210128],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.001450163,"threshold_uncertainty_score":0.002883494,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.02285422571795572,"score_gpt":0.2993504720093562,"score_spread":0.2764962462914005,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}