{"id":"W2099925167","doi":"10.1128/iai.01581-06","title":"<i>Burkholderia cenocepacia</i> Requires a Periplasmic HtrA Protease for Growth under Thermal and Osmotic Stress and for Survival In Vivo","year":2007,"lang":"en","type":"article","venue":"Infection and Immunity","topic":"Vibrio bacteria research studies","field":"Biochemistry, Genetics and Molecular Biology","cited_by":76,"is_retracted":false,"has_abstract":true,"ca_institutions":"Western University; University of Calgary","funders":"Department of Education of Guangdong Province","keywords":"Biology; Periplasmic space; Operon; Burkholderia cenocepacia; Complementation; Microbiology; Virulence; Proteases; Molecular biology; Gene; Mutant; Genetics; Escherichia coli; Biochemistry","routes":{"ca_aff":true,"ca_fund":false,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"codex-gemma-dda1882f352a","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0004093162,0.0001143762,0.0001249206,0.00005014583,0.0001994163,0.00004563546,0.0000315254,0.00008861659,0.000003041002],"category_scores_gemma":[0.0001968206,0.0001050713,0.00002735965,0.00004303383,0.0001545431,0.00001385944,0.00008510693,0.00007570504,6.931646e-8],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.00001340272,"about_ca_system_score_gemma":0.00002831193,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.0004444776,"about_ca_topic_score_gemma":0.0009948151,"domain_scores_codex":[0.9993634,0.00006082281,0.0001282792,0.0001837985,0.00004391883,0.0002198463],"domain_scores_gemma":[0.9996754,0.00005763451,0.00003733596,0.00009383125,0.00007645033,0.000059354],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"bench_or_experimental","study_design_gemma":"observational","study_design_scores_codex":[0.0006304453,0.00009154775,0.06257415,0.0002435648,0.0000525237,5.447022e-7,0.0002018163,0.0000019413,0.9345033,0.0001056529,0.00003937675,0.001555151],"study_design_scores_gemma":[0.002974719,0.001004321,0.5708647,0.00004740062,0.0000208077,0.00001221731,0.0005344184,0.00005977392,0.4221784,0.0003274613,0.001724779,0.0002509884],"study_design_candidate":"bench_or_experimental","study_design_consensus":null,"genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9975746,0.000277888,0.001166637,0.00009511871,0.00007655755,0.0006159597,0.00005104433,0.000008839541,0.0001333479],"genre_scores_gemma":[0.9991917,0.0004137307,0.0001171985,0.00004633994,0.00006651031,0.00007020812,0.00002371778,0.0000123106,0.00005828507],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.5123248,"threshold_uncertainty_score":0.4284682,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.02285422571795572,"score_gpt":0.2993504720093562,"score_spread":0.2764962462914005,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}