{"id":"W2099925178","doi":"10.1681/asn.2004030251","title":"Mechanical Stretch Induces Monocyte Chemoattractant Activity via an NF-κB-Dependent Monocyte Chemoattractant Protein-1-Mediated Pathway in Human Mesangial Cells","year":2005,"lang":"en","type":"article","venue":"Journal of the American Society of Nephrology","topic":"Peroxisome Proliferator-Activated Receptors","field":"Biochemistry, Genetics and Molecular Biology","cited_by":89,"is_retracted":false,"has_abstract":true,"ca_institutions":"Women's Health Research Institute","funders":"GlaxoSmithKline","keywords":"Monocyte; Rosiglitazone; Chemokine; Chemotaxis; Mesangial cell; Internal medicine; Endocrinology; Chemistry; Diabetic nephropathy; CCL2; Thiazolidinedione; Inflammation; Diabetes mellitus; Medicine; Receptor; Kidney; Type 2 diabetes","routes":{"ca_aff":true,"ca_fund":false,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"codex-gemma-dda1882f352a","candidate_categories":["metaepi_narrow"],"consensus_categories":[],"category_scores_codex":[0.0008306297,0.0003892173,0.00083902,0.00008216946,0.0001230352,0.00002321428,0.0009052411,0.000425102,0.00004100443],"category_scores_gemma":[0.00005520883,0.000303575,0.0005715548,0.0003149678,0.0005765212,0.00005283662,0.0002788044,0.001074481,0.000001980987],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.0002322783,"about_ca_system_score_gemma":0.0003762461,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.0001090818,"about_ca_topic_score_gemma":0.00006061577,"domain_scores_codex":[0.9971561,0.0004676433,0.0008546745,0.0004576487,0.0004817187,0.0005822133],"domain_scores_gemma":[0.9971004,0.00004940041,0.001877695,0.0005297558,0.0002152516,0.000227533],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","study_design_scores_codex":[0.0008514969,0.0007797811,0.0002895776,0.0000138912,0.0003110171,0.000005721121,0.0002705529,0.0001640663,0.9906903,0.00000225379,0.0002741824,0.006347139],"study_design_scores_gemma":[0.001452593,0.001599723,0.002326222,0.00002061673,0.00003880126,0.00009717091,0.0003483245,0.0003868801,0.9906209,0.0000338238,0.002778085,0.0002968791],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9974301,0.0001328477,0.0001862195,0.001727509,0.0001169002,0.0003573324,0.00002237904,0.00001173913,0.00001496944],"genre_scores_gemma":[0.995953,0.000194735,0.001858641,0.001249663,0.0006366337,0.00001570284,0.000009143232,0.00005390692,0.00002862493],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.00605026,"threshold_uncertainty_score":0.9999416,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.01481624589515089,"score_gpt":0.265700628394478,"score_spread":0.2508843824993271,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}