{"id":"W2099953361","doi":"10.1128/aac.44.12.3451-3455.2000","title":"Hepatitis B or Hepatitis C Virus Infection Is a Risk Factor for Severe Hepatic Cytolysis after Initiation of a Protease Inhibitor-Containing Antiretroviral Regimen in Human Immunodeficiency Virus-Infected Patients","year":2000,"lang":"en","type":"article","venue":"Antimicrobial Agents and Chemotherapy","topic":"HIV/AIDS drug development and treatment","field":"Medicine","cited_by":115,"is_retracted":false,"has_abstract":true,"ca_institutions":"Hotel Dieu Hospital","funders":"Wellcome Trust","keywords":"Virology; Protease; Cytolysis; Immunology; Hepatitis C virus; Protease inhibitor (pharmacology); Virus; Antibody; Hepatitis; Hepatitis B virus; Viral disease; Biology; Medicine; Internal medicine; Gastroenterology; Viral load; Enzyme; Antiretroviral therapy","routes":{"ca_aff":true,"ca_fund":false,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"codex-gemma-dda1882f352a","candidate_categories":["metaepi_narrow","insufficient_payload"],"consensus_categories":[],"category_scores_codex":[0.00009426711,0.0003099648,0.0005209247,0.0002445852,0.0001811251,0.00004304705,0.00004854564,0.0001488371,0.001210405],"category_scores_gemma":[0.00002101407,0.0002606141,0.0001538274,0.0003258616,0.00006176517,0.000244126,0.00002251067,0.0001271553,0.000008670899],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.0001619874,"about_ca_system_score_gemma":0.00007791656,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.004898632,"about_ca_topic_score_gemma":0.00122877,"domain_scores_codex":[0.9984161,0.00006678315,0.0005871303,0.0004071148,0.0002027781,0.0003200654],"domain_scores_gemma":[0.999338,0.00002809576,0.0002566712,0.0001880971,0.0001167705,0.00007238118],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"observational","study_design_gemma":"observational","study_design_scores_codex":[0.001782736,0.0009807826,0.9409576,0.0001448683,0.0001882558,0.00001312324,0.004281434,9.400208e-7,0.00398716,5.859091e-7,0.0002839304,0.0473786],"study_design_scores_gemma":[0.009177343,0.001341607,0.9552114,0.0004243181,0.0001434572,0.000006240283,0.00001180482,0.0001899093,0.03258752,0.00001594214,0.0005689106,0.0003215584],"study_design_candidate":"observational","study_design_consensus":"observational","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9975127,0.00001781202,0.00004076705,0.0001280867,0.0000464093,0.001643823,0.0005002603,0.00004105863,0.00006907056],"genre_scores_gemma":[0.9949898,0.002993605,0.0003406011,0.0006466674,0.00004203213,0.0001295447,0.0001957051,0.00004602576,0.000616],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.04705705,"threshold_uncertainty_score":0.9999846,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.009235378437476079,"score_gpt":0.2506006972361954,"score_spread":0.2413653187987193,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}