{"id":"W2099953361","doi":"10.1128/aac.44.12.3451-3455.2000","title":"Hepatitis B or Hepatitis C Virus Infection Is a Risk Factor for Severe Hepatic Cytolysis after Initiation of a Protease Inhibitor-Containing Antiretroviral Regimen in Human Immunodeficiency Virus-Infected Patients","year":2000,"lang":"en","type":"article","venue":"Antimicrobial Agents and Chemotherapy","topic":"HIV/AIDS drug development and treatment","field":"Medicine","cited_by":115,"is_retracted":false,"has_abstract":true,"ca_institutions":"Hotel Dieu Hospital","funders":"Wellcome Trust","keywords":"Virology; Protease; Cytolysis; Immunology; Hepatitis C virus; Protease inhibitor (pharmacology); Virus; Antibody; Hepatitis; Hepatitis B virus; Viral disease; Biology; Medicine; Internal medicine; Gastroenterology; Viral load; Enzyme; Antiretroviral therapy","routes":{"ca_aff":true,"ca_fund":false,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"metacan-v3-hybrid-931329e0061c","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0004968115,0.0002243772,0.0004288725,0.0003792553,0.0005194613,0.0006229672,0.0002066478,0.0005663573,0.00145853],"category_scores_gemma":[0.002760371,0.0003543082,0.0004173164,0.0004764307,0.0003418623,0.0004640436,0.0002998415,0.0007573424,0.0002046011],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.0001474007,"about_ca_system_score_gemma":0.0003128036,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.001851221,"about_ca_topic_score_gemma":0.002148916,"domain_scores_codex":[0.9996656,0.0001141077,0.00002958485,0.00005702939,0.0000612035,0.00007239995],"domain_scores_gemma":[0.9976214,0.0006262689,0.001038179,0.0001372026,0.0001034578,0.0004734341],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"observational","study_design_gemma":"observational","study_design_scores_codex":[0.0001965676,0.00003179324,0.9982923,0.00000429262,0.00003234517,0.0002031697,0.0000214844,0.00003104404,0.0001328058,0.000007452796,0.0000617055,0.0009849492],"study_design_scores_gemma":[0.00001938596,0.0002584735,0.9971309,0.000006654594,0.00004475745,0.001955685,0.00007989357,0.0002714499,0.00006735724,0.00002581024,0.0001351437,0.000004543777],"study_design_candidate":"observational","study_design_consensus":"observational","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9990985,0.0004110951,0.00004581496,0.00006476058,0.000006573837,0.000004462059,0.00005905298,0.000002694529,0.0003071514],"genre_scores_gemma":[0.9995283,0.0001617361,0.00003953457,0.00003735484,0.00002637579,0.000002453151,0.00008317272,9.047818e-7,0.0001201746],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.001851221,"threshold_uncertainty_score":0.004879236,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.009235378437476079,"score_gpt":0.2506006972361954,"score_spread":0.2413653187987193,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}