{"id":"W2099963529","doi":"10.1161/circresaha.110.238691","title":"Impaired Phosphatidylcholine Biosynthesis Reduces Atherosclerosis and Prevents Lipotoxic Cardiac Dysfunction in ApoE <sup>−/−</sup> Mice","year":2011,"lang":"en","type":"article","venue":"Circulation Research","topic":"Folate and B Vitamins Research","field":"Medicine","cited_by":62,"is_retracted":false,"has_abstract":true,"ca_institutions":"University of Alberta","funders":"Canadian Institutes of Health Research","keywords":"Internal medicine; Endocrinology; Apolipoprotein E; Apolipoprotein B; Lipoprotein; Cardiac function curve; Phosphatidylcholine; Biology; Cholesterol; Phospholipid; Chemistry; Medicine; Biochemistry; Disease; Heart failure","routes":{"ca_aff":true,"ca_fund":true,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"metacan-v3-hybrid-931329e0061c","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0005299205,0.001717458,0.0008254443,0.001636759,0.0003566703,0.0007740831,0.0007335676,0.001139806,0.002992691],"category_scores_gemma":[0.0003557804,0.000698995,0.0005985789,0.0003813437,0.0008830085,0.0005452626,0.0004382494,0.001562273,0.001308656],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.0004862864,"about_ca_system_score_gemma":0.0003941181,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.0008349661,"about_ca_topic_score_gemma":0.001172658,"domain_scores_codex":[0.9995164,0.00007366808,0.00009472926,0.0001178048,0.0001108541,0.00008660129],"domain_scores_gemma":[0.9988427,0.00008622361,0.0005069272,0.00008937527,0.0001010289,0.0003738256],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","study_design_scores_codex":[0.001120158,0.0002752375,0.0003231719,0.00006030334,0.00002380563,0.00006560046,0.00002411353,0.00007286698,0.9966085,0.0001096458,0.00009648889,0.001220128],"study_design_scores_gemma":[0.0005506853,0.002992637,0.01236815,0.00006939656,0.0001681822,0.0007951178,0.0001279472,0.001256787,0.977572,0.0002104541,0.003854234,0.00003445731],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9914147,0.00132312,0.003318497,0.0003693672,0.00008073106,0.00008107501,0.001594678,0.000515862,0.001301884],"genre_scores_gemma":[0.9720987,0.002400019,0.008217459,0.0004360501,0.00009960988,0.000333734,0.003262023,0.0005063593,0.01264595],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.002992691,"threshold_uncertainty_score":0.01001155,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.1164010715502019,"score_gpt":0.3408241895699511,"score_spread":0.2244231180197492,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}