{"id":"W2099968189","doi":"10.1128/mbio.00896-14","title":"A New Group of Phage Anti-CRISPR Genes Inhibits the Type I-E CRISPR-Cas System of Pseudomonas aeruginosa","year":2014,"lang":"en","type":"article","venue":"mBio","topic":"CRISPR and Genetic Engineering","field":"Biochemistry, Genetics and Molecular Biology","cited_by":280,"is_retracted":false,"has_abstract":true,"ca_institutions":"University of Toronto","funders":"Canadian Institutes of Health Research","keywords":"CRISPR; Gene; Biology; Pseudomonas aeruginosa; Genetics; Genome; Mobile genetic elements; CRISPR interference; Bacteriophage; Computational biology; Escherichia coli; Genome editing; Bacteria","routes":{"ca_aff":true,"ca_fund":true,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"metacan-v3-hybrid-931329e0061c","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0001807969,0.0007244449,0.0005847457,0.0007061556,0.0003007801,0.0004939413,0.0004880537,0.0006353862,0.001110362],"category_scores_gemma":[0.0003230045,0.000201137,0.0005973855,0.0003235848,0.0004029407,0.000404458,0.0003808246,0.0008549112,0.0006067216],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.000288486,"about_ca_system_score_gemma":0.0003139937,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.0003979072,"about_ca_topic_score_gemma":0.0004363382,"domain_scores_codex":[0.9995922,0.0000347633,0.00003530053,0.00009885091,0.0001802672,0.00005854595],"domain_scores_gemma":[0.9996901,0.00005400653,0.00009124669,0.00005409694,0.00005515465,0.00005539323],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","study_design_scores_codex":[0.00004632182,0.00004048465,0.000739897,0.00002977599,0.000007493372,0.0001159054,0.00002100933,0.0001019,0.9916647,0.0002302773,0.0001043255,0.006897865],"study_design_scores_gemma":[0.00001834225,0.0005691501,0.008254967,0.00000844284,0.00004984886,0.001513917,0.00003008661,0.001786506,0.9705302,0.000205281,0.01701006,0.00002314322],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9408001,0.003395554,0.04430253,0.0004900467,0.0001841431,0.0001539991,0.0008155085,0.001012384,0.008845743],"genre_scores_gemma":[0.9421911,0.001775049,0.04084826,0.0006601779,0.0000995223,0.0001779555,0.001986595,0.0001720799,0.01208922],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.001110362,"threshold_uncertainty_score":0.003714561,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.006637715501293056,"score_gpt":0.2594044039313103,"score_spread":0.2527666884300172,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}