{"id":"W2100011725","doi":"10.1083/jcb.201312029","title":"PAR-4/LKB1 regulates DNA replication during asynchronous division of the early <i>C. elegans</i> embryo","year":2014,"lang":"en","type":"article","venue":"The Journal of Cell Biology","topic":"Genetics, Aging, and Longevity in Model Organisms","field":"Biochemistry, Genetics and Molecular Biology","cited_by":26,"is_retracted":false,"has_abstract":true,"ca_institutions":"Université de Montréal; Institute for Research in Immunology and Cancer","funders":"Canadian Institutes of Health Research","keywords":"Biology; DNA replication; Caenorhabditis elegans; Cell cycle; Cell biology; Control of chromosome duplication; Cell division; Eukaryotic DNA replication; Embryo; Blastomere; Genetics; Origin recognition complex; Context (archaeology); Cell; DNA; Embryogenesis; Gene","routes":{"ca_aff":true,"ca_fund":true,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"metacan-v3-hybrid-931329e0061c","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0001087999,0.000289084,0.0001484674,0.0002084826,0.0002317631,0.000341209,0.0003024648,0.0002525857,0.0008077491],"category_scores_gemma":[0.0001738371,0.0002342352,0.0001165895,0.00004965489,0.0003026737,0.0002653535,0.0002826923,0.0003962126,0.0004785575],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.0005194811,"about_ca_system_score_gemma":0.0002809305,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.001430319,"about_ca_topic_score_gemma":0.002702867,"domain_scores_codex":[0.9998919,0.00001024548,0.000005871289,0.00003325468,0.00002879608,0.00002998402],"domain_scores_gemma":[0.9998206,0.00002107792,0.00007219081,0.00001287308,0.00002325851,0.00004996607],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","study_design_scores_codex":[0.00004683984,0.000006684713,0.0002283777,0.000009839658,9.652069e-7,0.00002913265,0.000005579888,0.00005023016,0.9990281,0.00007874313,0.00003752447,0.0004779965],"study_design_scores_gemma":[0.00002515146,0.00008818074,0.02395878,0.00000833044,0.000009592998,0.0001340184,0.00003421169,0.003152431,0.9711066,0.0001036246,0.001368774,0.0000103478],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9957182,0.000376445,0.001984718,0.00006812844,0.00001459064,0.000009766179,0.0001477035,0.0001156889,0.001564854],"genre_scores_gemma":[0.9966753,0.0001609694,0.001440697,0.00004099367,0.000004927379,0.00001925117,0.0001064498,0.00004541534,0.001506028],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.001430319,"threshold_uncertainty_score":0.003769159,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.004190848984598777,"score_gpt":0.2007292480112862,"score_spread":0.1965383990266875,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}