{"id":"W2100026340","doi":"10.1002/em.20639","title":"Pulmonary response to surface‐coated nanotitanium dioxide particles includes induction of acute phase response genes, inflammatory cascades, and changes in microRNAs: A toxicogenomic study","year":2011,"lang":"en","type":"article","venue":"Environmental and Molecular Mutagenesis","topic":"Nanoparticles: synthesis and applications","field":"Materials Science","cited_by":166,"is_retracted":false,"has_abstract":true,"ca_institutions":"Health Canada","funders":"Health Canada","keywords":"Inflammatory response; microRNA; Gene; Acute-phase protein; Biology; Inflammation; Toxicology; Genetics; Immunology","routes":{"ca_aff":true,"ca_fund":true,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"codex-gemma-dda1882f352a","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0007656414,0.0001828277,0.0002248291,0.0001097481,0.0001061481,0.00001894684,0.0001255005,0.00006168368,0.0000541527],"category_scores_gemma":[0.00001348704,0.0001768432,0.00002796224,0.000106623,0.0001541796,0.0000951762,0.0002177806,0.00003955607,0.00002020181],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.00006336185,"about_ca_system_score_gemma":0.00001738355,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.00009246872,"about_ca_topic_score_gemma":0.00003133284,"domain_scores_codex":[0.9984298,0.0004540511,0.0003075157,0.0004177566,0.0001528546,0.0002380376],"domain_scores_gemma":[0.9994315,0.00005250176,0.00009955495,0.0002721358,0.000005179512,0.0001391386],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","study_design_scores_codex":[0.002879578,0.0007368815,0.005860771,0.00000750558,0.00002910511,0.000133214,0.002034789,0.000006222711,0.9870369,0.000002364484,9.441933e-7,0.001271745],"study_design_scores_gemma":[0.00056843,0.0003583407,0.1522876,0.00001235177,0.00006737236,0.0000375526,0.001431747,0.000009628456,0.8449855,0.000009832387,0.00006368792,0.000167926],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9983467,0.0007604101,0.00002148706,0.0001082271,0.00002232434,0.0006221099,0.00009651529,0.0000205206,0.000001705782],"genre_scores_gemma":[0.9988639,0.0001240373,0.0008119486,0.00004396837,0.000006608584,0.0001020209,0.000003241441,0.00002509723,0.00001911328],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.1464268,"threshold_uncertainty_score":0.7211456,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.01522031237362073,"score_gpt":0.2345722879219467,"score_spread":0.219351975548326,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}