{"id":"W2100026340","doi":"10.1002/em.20639","title":"Pulmonary response to surface‐coated nanotitanium dioxide particles includes induction of acute phase response genes, inflammatory cascades, and changes in microRNAs: A toxicogenomic study","year":2011,"lang":"en","type":"article","venue":"Environmental and Molecular Mutagenesis","topic":"Nanoparticles: synthesis and applications","field":"Materials Science","cited_by":166,"is_retracted":false,"has_abstract":true,"ca_institutions":"Health Canada","funders":"Health Canada","keywords":"Inflammatory response; microRNA; Gene; Acute-phase protein; Biology; Inflammation; Toxicology; Genetics; Immunology","routes":{"ca_aff":true,"ca_fund":true,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"metacan-v3-hybrid-931329e0061c","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0001914417,0.0003460104,0.0003331822,0.0001937781,0.0001110687,0.0002491898,0.0001024564,0.0003608616,0.0008713047],"category_scores_gemma":[0.0001070114,0.000155676,0.0004058323,0.0001432783,0.0002530183,0.0001809675,0.0001699879,0.0003722175,0.0001722365],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.0001593753,"about_ca_system_score_gemma":0.0001242749,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.0001645701,"about_ca_topic_score_gemma":0.0003123403,"domain_scores_codex":[0.9998287,0.00002619865,0.00001109944,0.0000449961,0.00005334321,0.00003561162],"domain_scores_gemma":[0.9998775,0.00002293714,0.00003871323,0.0000116271,0.00002546546,0.00002372592],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","study_design_scores_codex":[0.0000651911,0.000007815456,0.0002197147,0.00001365938,0.000003009752,0.00001344861,0.000005547467,0.00001258129,0.9994174,0.000004752468,0.00000340134,0.0002335781],"study_design_scores_gemma":[0.000008550246,0.0006039921,0.01865355,0.000003168153,0.00002597017,0.0001599517,0.00004808268,0.0005962724,0.9794165,0.00002307554,0.000456286,0.000004668966],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9947456,0.001503146,0.002904424,0.00005389502,0.00002433506,0.00003710525,0.0002317286,0.00003623213,0.0004635997],"genre_scores_gemma":[0.9934793,0.0009628698,0.003168426,0.00009740433,0.00002191477,0.0001179518,0.0004208055,0.00001500199,0.001716435],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.0008713047,"threshold_uncertainty_score":0.002914786,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.01522031237362073,"score_gpt":0.2345722879219467,"score_spread":0.219351975548326,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}