{"id":"W2100066024","doi":"10.1186/1710-1492-9-16","title":"A four-way, double-blind, randomized, placebo controlled study to determine the efficacy and speed of azelastine nasal spray, versus loratadine, and cetirizine in adult subjects with allergen-induced seasonal allergic rhinitis","year":2013,"lang":"en","type":"article","venue":"Allergy Asthma and Clinical Immunology","topic":"Allergic Rhinitis and Sensitization","field":"Medicine","cited_by":35,"is_retracted":false,"has_abstract":true,"ca_institutions":"Kingston General Hospital; Queen's University","funders":"","keywords":"Azelastine; Cetirizine; Loratadine; Medicine; Onset of action; Placebo; Crossover study; Nasal spray; Antihistamine; Terfenadine; Pharmacology; Anesthesia; Nasal administration","routes":{"ca_aff":true,"ca_fund":false,"ca_venue":true,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"metacan-v3-hybrid-931329e0061c","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.003087312,0.001409827,0.004769449,0.0006452934,0.0008117584,0.0008317014,0.001101852,0.00238504,0.007615964],"category_scores_gemma":[0.003292488,0.0009823546,0.001390669,0.0004971543,0.001795738,0.001117777,0.0003941889,0.002207455,0.001090241],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.0005074653,"about_ca_system_score_gemma":0.001530896,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.0008216951,"about_ca_topic_score_gemma":0.001665302,"domain_scores_codex":[0.9985577,0.0006643006,0.0001602516,0.0002790835,0.0001641824,0.0001744898],"domain_scores_gemma":[0.9976572,0.000800544,0.0003864404,0.0001759558,0.0002575317,0.0007224364],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"randomized_trial","study_design_gemma":"randomized_trial","study_design_scores_codex":[0.9624516,0.02373477,0.0005370064,0.0004895831,0.0003493121,0.00003142759,0.00007428203,0.00007163581,0.004398888,0.00003935998,0.0002336876,0.007588355],"study_design_scores_gemma":[0.7865472,0.2099277,0.002452261,0.00001529209,0.0001992038,0.00001671906,0.00001881411,0.0001494744,0.0003333252,0.0000346612,0.0002946876,0.00001071649],"study_design_candidate":"randomized_trial","study_design_consensus":"randomized_trial","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.987882,0.002084846,0.0007226412,0.0003432204,0.0007374684,0.006753684,0.0005252085,0.0001021748,0.0008487271],"genre_scores_gemma":[0.9756076,0.002271779,0.004004282,0.001150397,0.001139776,0.01150981,0.0007002428,0.00002601484,0.00359012],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.007615964,"threshold_uncertainty_score":0.02547789,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.04047739838376077,"score_gpt":0.3074269103265835,"score_spread":0.2669495119428228,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}