{"id":"W2100066024","doi":"10.1186/1710-1492-9-16","title":"A four-way, double-blind, randomized, placebo controlled study to determine the efficacy and speed of azelastine nasal spray, versus loratadine, and cetirizine in adult subjects with allergen-induced seasonal allergic rhinitis","year":2013,"lang":"en","type":"article","venue":"Allergy Asthma and Clinical Immunology","topic":"Allergic Rhinitis and Sensitization","field":"Medicine","cited_by":35,"is_retracted":false,"has_abstract":true,"ca_institutions":"Kingston General Hospital; Queen's University","funders":"","keywords":"Azelastine; Cetirizine; Loratadine; Medicine; Onset of action; Placebo; Crossover study; Nasal spray; Antihistamine; Terfenadine; Pharmacology; Anesthesia; Nasal administration","routes":{"ca_aff":true,"ca_fund":false,"ca_venue":true,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"codex-gemma-dda1882f352a","candidate_categories":["metaepi_narrow"],"consensus_categories":[],"category_scores_codex":[0.001099897,0.000478516,0.002161579,0.0002121745,0.0001405309,0.00005914496,0.0001629286,0.0002933163,0.0001725889],"category_scores_gemma":[0.001375391,0.0002998389,0.0001460305,0.0002981703,0.0007110852,0.0001416934,0.0002401179,0.0006131122,0.00001564105],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.0000207927,"about_ca_system_score_gemma":0.0001253439,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.0008003507,"about_ca_topic_score_gemma":0.004001194,"domain_scores_codex":[0.9960974,0.0008297149,0.001467027,0.0007525766,0.0003484584,0.0005047841],"domain_scores_gemma":[0.9945945,0.003733667,0.0004416767,0.0004300801,0.0004930453,0.0003070014],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"randomized_trial","study_design_gemma":"randomized_trial","study_design_scores_codex":[0.9841227,0.001425917,0.002712746,0.00001836765,0.003258131,0.0002959049,0.00143502,0.0000157013,0.0007146871,0.0003851253,0.0001303108,0.005485371],"study_design_scores_gemma":[0.8653301,0.01100978,0.1180267,0.0001463339,0.0002297705,0.0003767483,0.001484576,0.002848494,0.00004394219,0.00002501132,0.0001321501,0.0003463474],"study_design_candidate":"randomized_trial","study_design_consensus":"randomized_trial","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9894866,0.0005401001,0.00003903505,0.004625844,0.0002966037,0.004418113,0.000003134915,0.00003555317,0.0005550329],"genre_scores_gemma":[0.9963461,0.002262377,0.0002338052,0.0005027821,0.0001786429,0.0001614167,0.00003364367,0.00004775557,0.0002334793],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.1187926,"threshold_uncertainty_score":0.9999454,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.04047739838376077,"score_gpt":0.3074269103265835,"score_spread":0.2669495119428228,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}