{"id":"W2100082084","doi":"10.1186/1475-2859-11-160","title":"Effects of synthetic cohesin-containing scaffold protein architecture on binding dockerin-enzyme fusions on the surface of Lactococcus lactis","year":2012,"lang":"en","type":"article","venue":"Microbial Cell Factories","topic":"Biochemical and Structural Characterization","field":"Biochemistry, Genetics and Molecular Biology","cited_by":24,"is_retracted":false,"has_abstract":true,"ca_institutions":"Concordia University","funders":"Natural Sciences and Engineering Research Council of Canada; Fonds Québécois de la Recherche sur la Nature et les Technologies","keywords":"Cellulosome; Cohesin; Clostridium thermocellum; Lactococcus lactis; Biochemistry; Protein engineering; Chemistry; Fusion protein; Enzyme; Escherichia coli; Recombinant DNA; Biology; Cell biology; Cellulase; Bacteria; Chromatin; DNA; Genetics","routes":{"ca_aff":true,"ca_fund":true,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"metacan-v3-hybrid-931329e0061c","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0001686684,0.0004244763,0.0002281368,0.0001496071,0.0001130394,0.0004303033,0.0002829967,0.000266073,0.0006811146],"category_scores_gemma":[0.0002459597,0.000149254,0.0001952083,0.0001661264,0.0001957184,0.0001567628,0.0002714482,0.0003446575,0.00022028],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.0004950112,"about_ca_system_score_gemma":0.0001568809,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.00170718,"about_ca_topic_score_gemma":0.001977704,"domain_scores_codex":[0.9998185,0.00002986305,0.00001788431,0.00003727549,0.00005150782,0.00004499255],"domain_scores_gemma":[0.9998259,0.00004505407,0.00005276566,0.00001694372,0.00001845522,0.00004082433],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","study_design_scores_codex":[0.00007691913,0.00002307829,0.0001384363,0.00001678802,0.000006393696,0.00002370825,0.00001402376,0.0001753399,0.9991892,0.00002139514,0.000009641816,0.0003049964],"study_design_scores_gemma":[0.000007586195,0.0001622846,0.00105267,0.000002702345,0.00001064918,0.00004754259,0.00002518126,0.001143118,0.9971977,0.00000499044,0.0003412361,0.000004188816],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9989591,0.0002000695,0.0005430683,0.00001417479,0.000004645543,0.000006074019,0.00003165287,0.00001939993,0.0002218484],"genre_scores_gemma":[0.9984406,0.0001425777,0.0008706073,0.00001569107,0.000001327695,0.00000753856,0.0001062438,0.00001324662,0.0004022679],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.00170718,"threshold_uncertainty_score":0.003591597,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.006573882260424019,"score_gpt":0.1985842083557566,"score_spread":0.1920103260953326,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}