{"id":"W2100082084","doi":"10.1186/1475-2859-11-160","title":"Effects of synthetic cohesin-containing scaffold protein architecture on binding dockerin-enzyme fusions on the surface of Lactococcus lactis","year":2012,"lang":"en","type":"article","venue":"Microbial Cell Factories","topic":"Biochemical and Structural Characterization","field":"Biochemistry, Genetics and Molecular Biology","cited_by":24,"is_retracted":false,"has_abstract":true,"ca_institutions":"Concordia University","funders":"Natural Sciences and Engineering Research Council of Canada; Fonds Québécois de la Recherche sur la Nature et les Technologies","keywords":"Cellulosome; Cohesin; Clostridium thermocellum; Lactococcus lactis; Biochemistry; Protein engineering; Chemistry; Fusion protein; Enzyme; Escherichia coli; Recombinant DNA; Biology; Cell biology; Cellulase; Bacteria; Chromatin; DNA; Genetics","routes":{"ca_aff":true,"ca_fund":true,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"codex-gemma-dda1882f352a","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.00007041316,0.0001971322,0.0001976848,0.00002500325,0.00009283978,0.00001404497,0.000166997,0.0001689174,0.00002569106],"category_scores_gemma":[0.00008129877,0.0001300966,0.00008863433,0.00008994956,0.0001103792,0.000005396137,0.0000814438,0.0001447969,0.000003913032],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.00001562847,"about_ca_system_score_gemma":0.00002278414,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.00001625447,"about_ca_topic_score_gemma":0.000002614939,"domain_scores_codex":[0.9991507,0.00009427026,0.0001966638,0.0001935684,0.0001128506,0.0002519444],"domain_scores_gemma":[0.9994163,0.00009103178,0.0001697728,0.0002203654,0.00004481869,0.0000576974],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","study_design_scores_codex":[0.0002628456,0.00006664959,0.0004959792,0.0001342511,0.00002230124,3.322081e-7,0.0002573117,0.00000859332,0.9984301,0.00007407691,0.00007503347,0.0001725666],"study_design_scores_gemma":[0.0002058135,0.000364958,0.001973387,0.00009321912,0.00001770347,0.000001397119,0.00004053558,5.075728e-7,0.995347,0.00001207569,0.001794026,0.000149359],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9988495,0.000111712,0.00005151722,0.0001006186,0.0002122325,0.0004543472,0.00007251542,0.00001025514,0.0001372665],"genre_scores_gemma":[0.9994351,0.00001256001,0.00007565463,0.00004992109,0.0001393679,0.000009611564,0.0000702659,0.00002030878,0.0001872572],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.003083041,"threshold_uncertainty_score":0.5305184,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.006573882260424019,"score_gpt":0.1985842083557566,"score_spread":0.1920103260953326,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}