{"id":"W2100116291","doi":"10.1093/hmg/ddt489","title":"DNase hypersensitive sites and association with multiple sclerosis","year":2013,"lang":"en","type":"article","venue":"Human Molecular Genetics","topic":"Immune Cell Function and Interaction","field":"Immunology and Microbiology","cited_by":25,"is_retracted":false,"has_abstract":true,"ca_institutions":"Simon Fraser University","funders":"National Institute for Health and Care Research","keywords":"Biology; Single-nucleotide polymorphism; Genome-wide association study; Genetics; Immune system; Genetic association; Cytotoxic T cell; Gene; Immunology; Molecular biology; Genotype; In vitro","routes":{"ca_aff":true,"ca_fund":false,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"metacan-v3-hybrid-931329e0061c","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0006570836,0.0002429556,0.0003197619,0.001006138,0.0001996052,0.0004119411,0.0002068362,0.0003780296,0.00610677],"category_scores_gemma":[0.002433409,0.0001466185,0.0004870238,0.001353103,0.0002331225,0.0001340813,0.0003077243,0.0004043857,0.000449888],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.0001368691,"about_ca_system_score_gemma":0.0001364731,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.0008456031,"about_ca_topic_score_gemma":0.001161103,"domain_scores_codex":[0.9994153,0.000189875,0.00005853994,0.000211967,0.000078464,0.00004585541],"domain_scores_gemma":[0.9973008,0.00143196,0.0008048326,0.0001585328,0.0001070573,0.0001968974],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"observational","study_design_gemma":"observational","study_design_scores_codex":[0.002009667,0.00008687852,0.9394885,0.0004022336,0.001360523,0.0005037474,0.0001216659,0.0008521732,0.02806615,0.0003190816,0.0009848669,0.02580456],"study_design_scores_gemma":[0.00005695267,0.0001779049,0.9917873,0.00004032818,0.000287757,0.001993949,0.00004929294,0.0009273421,0.002099983,0.0008288469,0.001731834,0.00001864373],"study_design_candidate":"observational","study_design_consensus":"observational","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9883438,0.005563493,0.001615983,0.0001333832,0.00002360126,0.00001410994,0.003040631,0.00009584252,0.00116907],"genre_scores_gemma":[0.9956534,0.0007878534,0.00157447,0.00005178684,0.00002253502,0.0000150799,0.00138266,0.00001305505,0.0004992039],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.00610677,"threshold_uncertainty_score":0.02042913,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.01477062942815694,"score_gpt":0.1994420999643125,"score_spread":0.1846714705361555,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}