{"id":"W2100137309","doi":"10.1128/aac.48.10.3758-3764.2004","title":"Complete Nucleotide Sequence of a 92-Kilobase Plasmid Harboring the CTX-M-15 Extended-Spectrum Beta-Lactamase Involved in an Outbreak in Long-Term-Care Facilities in Toronto, Canada","year":2004,"lang":"en","type":"article","venue":"Antimicrobial Agents and Chemotherapy","topic":"Antibiotic Resistance in Bacteria","field":"Biochemistry, Genetics and Molecular Biology","cited_by":384,"is_retracted":false,"has_abstract":true,"ca_institutions":"University Health Network; Vancouver General Hospital; Health Canada","funders":"","keywords":"Plasmid; Transposable element; Biology; Insertion sequence; Escherichia coli; Tetracycline; Gene; Beta-lactamase; Point mutation; Nucleic acid sequence; Outbreak; Transposition (logic); Genetics; Virology; Mutation; Genome; Antibiotics","routes":{"ca_aff":true,"ca_fund":false,"ca_venue":false,"about_ca":true,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"codex-gemma-dda1882f352a","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0001000216,0.0002341855,0.0002889413,0.00003427497,0.00004956235,0.00003701285,0.0002765791,0.0001030337,0.00004198555],"category_scores_gemma":[0.000006788785,0.0002031507,0.00004775997,0.00007989885,0.0001686642,0.00002583115,0.00006290784,0.0001111173,3.351824e-7],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.0002361302,"about_ca_system_score_gemma":0.0002333551,"about_ca_topic_candidate":true,"about_ca_topic_consensus":true,"about_ca_topic_score_codex":0.2204776,"about_ca_topic_score_gemma":0.9041356,"domain_scores_codex":[0.9986891,0.00005778271,0.0003831607,0.0004015963,0.0001148656,0.0003534644],"domain_scores_gemma":[0.9994624,0.00000814152,0.0001115548,0.0003290943,0.00002984622,0.0000590115],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"observational","study_design_gemma":"observational","study_design_scores_codex":[0.000396417,0.0001729962,0.6341892,0.000144281,0.00003061602,0.00006789855,0.0009603358,0.000100378,0.3631557,0.00006652875,0.00008948737,0.0006262313],"study_design_scores_gemma":[0.002528555,0.0001340188,0.8910537,0.0002220089,0.000005886486,0.000006426597,0.001231977,0.00001426551,0.1037243,0.00002122488,0.0007405825,0.0003171282],"study_design_candidate":"observational","study_design_consensus":"observational","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9986539,0.000207259,0.00001717286,0.0004215552,0.00007558738,0.0003022775,0.0002281976,0.000004801521,0.00008928515],"genre_scores_gemma":[0.9978048,0.0008709406,0.0001261193,0.0009562111,0.00003550526,0.000004301968,0.0001510982,0.00002322861,0.00002784669],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.6836581,"threshold_uncertainty_score":0.8284246,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.01282471187842423,"score_gpt":0.2507708408021581,"score_spread":0.2379461289237339,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}