{"id":"W2100137309","doi":"10.1128/aac.48.10.3758-3764.2004","title":"Complete Nucleotide Sequence of a 92-Kilobase Plasmid Harboring the CTX-M-15 Extended-Spectrum Beta-Lactamase Involved in an Outbreak in Long-Term-Care Facilities in Toronto, Canada","year":2004,"lang":"en","type":"article","venue":"Antimicrobial Agents and Chemotherapy","topic":"Antibiotic Resistance in Bacteria","field":"Biochemistry, Genetics and Molecular Biology","cited_by":384,"is_retracted":false,"has_abstract":true,"ca_institutions":"University Health Network; Vancouver General Hospital; Health Canada","funders":"","keywords":"Plasmid; Transposable element; Biology; Insertion sequence; Escherichia coli; Tetracycline; Gene; Beta-lactamase; Point mutation; Nucleic acid sequence; Outbreak; Transposition (logic); Genetics; Virology; Mutation; Genome; Antibiotics","routes":{"ca_aff":true,"ca_fund":false,"ca_venue":false,"about_ca":true,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"metacan-v3-hybrid-931329e0061c","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.00007409722,0.0005562331,0.0004395493,0.0009116412,0.0007491072,0.0004532907,0.0005454019,0.0003960319,0.003063091],"category_scores_gemma":[0.0003595229,0.0002388756,0.000410264,0.001580059,0.0003536304,0.0001224816,0.0001820407,0.0005794256,0.001506213],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.003247565,"about_ca_system_score_gemma":0.003316895,"about_ca_topic_candidate":true,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.3307266,"about_ca_topic_score_gemma":0.3974745,"domain_scores_codex":[0.9998494,0.000008155284,0.00001503613,0.00002943824,0.00006772774,0.00003022938],"domain_scores_gemma":[0.9996194,0.00003631654,0.00006815205,0.00001554326,0.0001381796,0.0001223596],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"bench_or_experimental","study_design_gemma":"observational","study_design_scores_codex":[0.001565341,0.0003882522,0.02910974,0.0009593906,0.00007778069,0.003637573,0.001694362,0.001238175,0.927376,0.0009763657,0.005126308,0.02785074],"study_design_scores_gemma":[0.0002872508,0.0009961288,0.7977574,0.0004283443,0.0002339457,0.002497967,0.001522117,0.002537758,0.08682478,0.0002033065,0.106577,0.0001339191],"study_design_candidate":"observational","study_design_consensus":null,"genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.8714359,0.002157514,0.007161241,0.0004921415,0.0002559714,0.001116879,0.1042535,0.0002495554,0.01287727],"genre_scores_gemma":[0.8111611,0.001486507,0.0137134,0.0002775727,0.00004889807,0.000228729,0.1626365,0.00008567567,0.01036154],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.6692734,"threshold_uncertainty_score":0.6576031,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.01282471187842423,"score_gpt":0.2507708408021581,"score_spread":0.2379461289237339,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}