{"id":"W2100256576","doi":"10.1261/rna.2124610","title":"OB-fold domain of KREPA4 mediates high-affinity interaction with guide RNA and possesses annealing activity","year":2010,"lang":"en","type":"article","venue":"RNA","topic":"RNA and protein synthesis mechanisms","field":"Biochemistry, Genetics and Molecular Biology","cited_by":17,"is_retracted":false,"has_abstract":true,"ca_institutions":"McGill University","funders":"Natural Sciences and Engineering Research Council of Canada","keywords":"Biology; Fold (higher-order function); RNA; Computational biology; Cell biology; Molecular biology; Biophysics; Genetics; Gene","routes":{"ca_aff":true,"ca_fund":true,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"codex-gemma-dda1882f352a","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0002288848,0.0001209781,0.0001427551,0.00002960317,0.00006029684,0.00002329048,0.00008420493,0.000127359,0.0000344097],"category_scores_gemma":[0.0001233863,0.00009641464,0.00003353539,0.00004299645,0.00006201129,0.00001167932,0.00005746937,0.00009871434,0.000001712889],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.000004073668,"about_ca_system_score_gemma":0.00004045979,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.0002301355,"about_ca_topic_score_gemma":0.0002511885,"domain_scores_codex":[0.9993544,0.00004954369,0.0001350127,0.0002262712,0.0001006563,0.0001341437],"domain_scores_gemma":[0.9994391,0.00003707288,0.0001446644,0.0002460608,0.00007283175,0.00006022286],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","study_design_scores_codex":[0.0001758483,0.00003571756,0.0003700144,0.00003106923,0.00003331113,0.000003035585,0.00002940782,0.000004347137,0.9922128,0.0001597707,0.00008679131,0.00685784],"study_design_scores_gemma":[0.0002518928,0.0002188673,0.001495527,0.0000222371,0.0000148106,0.00001876835,0.00004884023,0.000008046895,0.994583,0.0004705339,0.002744776,0.0001226634],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9974405,0.00004227942,0.0008373849,0.0001500771,0.0001581201,0.0004096106,0.00001276906,0.000012204,0.0009370466],"genre_scores_gemma":[0.99423,0.00004701761,0.005324441,0.0000343391,0.0001721794,0.00008141267,0.00001086824,0.00001525634,0.0000844738],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.006735176,"threshold_uncertainty_score":0.3931675,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.007296610152796638,"score_gpt":0.2452078981310097,"score_spread":0.237911287978213,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}