{"id":"W2100256576","doi":"10.1261/rna.2124610","title":"OB-fold domain of KREPA4 mediates high-affinity interaction with guide RNA and possesses annealing activity","year":2010,"lang":"en","type":"article","venue":"RNA","topic":"RNA and protein synthesis mechanisms","field":"Biochemistry, Genetics and Molecular Biology","cited_by":17,"is_retracted":false,"has_abstract":true,"ca_institutions":"McGill University","funders":"Natural Sciences and Engineering Research Council of Canada","keywords":"Biology; Fold (higher-order function); RNA; Computational biology; Cell biology; Molecular biology; Biophysics; Genetics; Gene","routes":{"ca_aff":true,"ca_fund":true,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"metacan-v3-hybrid-931329e0061c","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.00007811878,0.0003186873,0.0002249082,0.0001223673,0.0001201856,0.0001955277,0.0001829993,0.0001683099,0.001225401],"category_scores_gemma":[0.0001376403,0.0001040419,0.00028458,0.00008372319,0.0001716283,0.0001371392,0.0001979142,0.0003082478,0.0007364629],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.0002236875,"about_ca_system_score_gemma":0.0001250137,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.0004751717,"about_ca_topic_score_gemma":0.0004355344,"domain_scores_codex":[0.9999459,0.00001051146,0.000003778368,0.00001149111,0.00001291451,0.00001545533],"domain_scores_gemma":[0.9998976,0.00002137347,0.00002519419,0.00001452631,0.0000149719,0.00002636946],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","study_design_scores_codex":[0.00005338382,0.000009260055,0.0003944242,0.00001832156,0.000002548704,0.00004275865,0.000008345809,0.00004989095,0.998547,0.00006648267,0.00001588795,0.0007917788],"study_design_scores_gemma":[0.00001004316,0.00007470301,0.007564655,0.000003601066,0.00001053071,0.0004769896,0.00002866215,0.001465835,0.9884819,0.00003913827,0.001840049,0.000003960153],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9959151,0.000271225,0.003078685,0.00003382421,0.00000466088,0.00000700704,0.0001409348,0.00005155271,0.0004970304],"genre_scores_gemma":[0.9943817,0.00011706,0.003001793,0.00002868301,0.000004558695,0.00001092118,0.0008851879,0.00002855239,0.001541643],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.001225401,"threshold_uncertainty_score":0.004099429,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.007296610152796638,"score_gpt":0.2452078981310097,"score_spread":0.237911287978213,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}