{"id":"W2100280809","doi":"10.1016/j.neuron.2014.07.023","title":"Unique Interweaved Microtubule Scaffold Mediates Osmosensory Transduction via Physical Interaction with TRPV1","year":2014,"lang":"en","type":"article","venue":"Neuron","topic":"Planarian Biology and Electrostimulation","field":"Biochemistry, Genetics and Molecular Biology","cited_by":110,"is_retracted":false,"has_abstract":false,"ca_institutions":"McGill University Health Centre; Montreal General Hospital","funders":"Canadian Institutes of Health Research","keywords":"Scaffold protein; Transduction (biophysics); Microtubule; Scaffold; Cell biology; TRPV1; Signal transduction; Chemistry; Neuroscience; Biophysics; Biology; Computer science; Receptor; Transient receptor potential channel; Biochemistry","routes":{"ca_aff":true,"ca_fund":true,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"codex-gemma-dda1882f352a","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.00006375976,0.0001231299,0.0001018758,0.00003267813,0.0000580514,0.00001015053,0.00006736202,0.0001125722,0.000007742474],"category_scores_gemma":[0.00002094791,0.0001047266,0.00004177395,0.0000462869,0.00005144543,0.000007951068,0.00001095198,0.0001155426,0.00001572181],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.000009456142,"about_ca_system_score_gemma":0.00001177128,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.000009801053,"about_ca_topic_score_gemma":0.00003903266,"domain_scores_codex":[0.9993122,0.0001173769,0.0000937412,0.0002717376,0.00004880818,0.0001561643],"domain_scores_gemma":[0.9997049,0.00002027016,0.00005178636,0.0001506816,0.00003218119,0.000040188],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","study_design_scores_codex":[0.0004544456,0.00005365514,0.0006005748,0.00000641986,0.00001764806,9.432455e-7,0.00004089306,0.0002118986,0.9948118,0.00002358513,0.0005935587,0.003184566],"study_design_scores_gemma":[0.0005085403,0.001254787,0.006621421,0.000009431368,0.00002362656,0.00005741705,0.000007080684,0.002178236,0.9744723,0.0001029909,0.01461374,0.0001503995],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9906756,0.00001389686,0.007857634,0.0007692761,0.0001635327,0.0001096583,0.000003071949,0.00002802029,0.0003792549],"genre_scores_gemma":[0.9985116,0.0000156074,0.00006453905,0.000631975,0.0003694413,0.00001008293,0.0002374304,0.0000164202,0.0001429723],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.02033948,"threshold_uncertainty_score":0.4270627,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.005302377714413686,"score_gpt":0.2173766084390713,"score_spread":0.2120742307246576,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}