{"id":"W2100285669","doi":"10.18632/oncotarget.1757","title":"Spherical nucleic acids for precision medicine","year":2013,"lang":"en","type":"editorial","venue":"Oncotarget","topic":"Advanced biosensing and bioanalysis techniques","field":"Biochemistry, Genetics and Molecular Biology","cited_by":9,"is_retracted":false,"has_abstract":true,"ca_institutions":"Western University","funders":"","keywords":"RNA interference; Nucleic acid; Small interfering RNA; Oligonucleotide; Computational biology; Nuclease; Cancer; Transfection; Biology; RNA; DNA; Cancer research; Gene; Genetics","routes":{"ca_aff":true,"ca_fund":false,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"metacan-v3-hybrid-931329e0061c","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0006323758,0.0007577557,0.0006415711,0.0007475943,0.000542635,0.001875782,0.0007654517,0.002022709,0.02350058],"category_scores_gemma":[0.001058623,0.000341958,0.0004484586,0.0006414191,0.001178648,0.00183945,0.001909499,0.002646478,0.01290051],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.001493207,"about_ca_system_score_gemma":0.0006198139,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.0004998501,"about_ca_topic_score_gemma":0.0004960948,"domain_scores_codex":[0.9993712,0.0001060506,0.00002640499,0.0001520736,0.0003024475,0.00004177719],"domain_scores_gemma":[0.9996382,0.0001046382,0.00006495104,0.00005866971,0.0000890072,0.00004456155],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"theoretical_or_conceptual","study_design_gemma":"not_applicable","study_design_scores_codex":[0.0001475196,0.00007653451,0.0003076705,0.001883999,0.00005202711,0.0003538113,0.0002158766,0.004479486,0.1328862,0.4533742,0.07624672,0.329976],"study_design_scores_gemma":[0.00003137562,0.0001733765,0.0001496482,0.0002278881,0.00001754205,0.0004507951,0.00004341409,0.003382825,0.04160878,0.05259846,0.9012706,0.00004517283],"study_design_candidate":"not_applicable","study_design_consensus":null,"genre_codex":"methods","genre_gemma":"editorial","genre_scores_codex":[0.01288831,0.2876048,0.3505935,0.01645513,0.01057744,0.0006255239,0.001968321,0.003755155,0.3155318],"genre_scores_gemma":[0.332157,0.1892939,0.2792173,0.0113678,0.004987774,0.001558188,0.002344065,0.0008827379,0.1781912],"genre_candidate":"editorial","genre_consensus":null,"teacher_disagreement_score":0.02350058,"threshold_uncertainty_score":0.07861733,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.007956839203619715,"score_gpt":0.3004229324552514,"score_spread":0.2924660932516317,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}