{"id":"W2100314653","doi":"10.1186/1742-4690-10-s1-p35","title":"HIV-1 replication changes the function of the PKR activator PACT","year":2013,"lang":"en","type":"article","venue":"Retrovirology","topic":"RNA regulation and disease","field":"Biochemistry, Genetics and Molecular Biology","cited_by":0,"is_retracted":false,"has_abstract":true,"ca_institutions":"McGill University Health Centre; McGill University","funders":"Styrelsen för Internationellt Utvecklingssamarbete","keywords":"Pact; Activator (genetics); Replication (statistics); Human immunodeficiency virus (HIV); Virology; Medicine; Computational biology; Biology; Internal medicine; Political science; Receptor","routes":{"ca_aff":true,"ca_fund":false,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"codex-gemma-dda1882f352a","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.00007793424,0.00005909243,0.00005771668,0.0000128671,0.00006074138,0.000006125648,0.0001363921,0.00009268046,0.0001175101],"category_scores_gemma":[0.0001080825,0.00003282066,0.00005359956,0.00005631398,0.0001005215,0.000002498382,0.00005188563,0.00004435326,0.00002575114],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.000006004374,"about_ca_system_score_gemma":0.00002327468,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.0000153214,"about_ca_topic_score_gemma":0.000007385478,"domain_scores_codex":[0.9995098,0.00008673842,0.00008494916,0.0001617906,0.00006270916,0.00009398245],"domain_scores_gemma":[0.9992144,0.00001220303,0.0001007509,0.0005980603,0.00004671929,0.00002786634],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"bench_or_experimental","study_design_gemma":"observational","study_design_scores_codex":[0.0000618402,0.00002186582,0.03561917,0.00000418364,0.00002074729,3.020762e-8,0.00001253598,0.00001463321,0.9490674,0.0003894895,0.0104443,0.004343801],"study_design_scores_gemma":[0.0002540098,0.0001628712,0.8596082,0.000001525333,0.00001997801,0.000003651694,0.00003564412,0.00009583628,0.08223742,0.0002487767,0.05727448,0.00005756829],"study_design_candidate":"bench_or_experimental","study_design_consensus":null,"genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9926248,0.0001322888,0.0003002556,0.005835158,0.0001072499,0.0001970887,0.000005556039,0.000006328678,0.0007913213],"genre_scores_gemma":[0.9969815,0.00002255556,0.00001172451,0.001319216,0.0001416898,0.00003912146,0.0000287688,0.000006912574,0.0014485],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.86683,"threshold_uncertainty_score":0.1338388,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.0079126652422697,"score_gpt":0.2218492279386508,"score_spread":0.2139365626963811,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}