{"id":"W2100387642","doi":"10.1128/ec.1.1.75-84.2002","title":"Adenylyl Cyclase Functions Downstream of the Gα Protein Gpa1 and Controls Mating and Pathogenicity of <i>Cryptococcus neoformans</i>","year":2002,"lang":"en","type":"article","venue":"Eukaryotic Cell","topic":"Fungal Infections and Studies","field":"Medicine","cited_by":204,"is_retracted":false,"has_abstract":true,"ca_institutions":"University of British Columbia","funders":"National Institute of Allergy and Infectious Diseases; Canadian Institutes of Health Research; Infectious Diseases Society of America; Howard Hughes Medical Institute","keywords":"Cryptococcus neoformans; Biology; Adenylyl cyclase; Mating; ADCY9; Cell biology; Pathogenicity; Gs alpha subunit; Cryptococcus; Fungal protein; Microbiology; Genetics; Virology; Saccharomyces cerevisiae; Signal transduction; Gene","routes":{"ca_aff":true,"ca_fund":true,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"metacan-v3-hybrid-931329e0061c","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.00005772884,0.0004692086,0.0001455423,0.0002627634,0.0002186151,0.0003440075,0.0001670392,0.0002172472,0.0009758333],"category_scores_gemma":[0.00008977199,0.0001245715,0.0001991503,0.0001475416,0.0002932078,0.0001378822,0.0002741947,0.0003763545,0.0004587415],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.0006416515,"about_ca_system_score_gemma":0.0002868727,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.003618879,"about_ca_topic_score_gemma":0.002993091,"domain_scores_codex":[0.9999,0.000008425298,0.00000422011,0.00002592068,0.0000218707,0.00003973403],"domain_scores_gemma":[0.9999256,0.000004962214,0.00002408639,0.000006800711,0.000008952249,0.00002965532],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","study_design_scores_codex":[0.00004845032,0.000008460728,0.0005597781,0.00001450888,0.000001610776,0.00009646154,0.00001153311,0.00005969902,0.9977684,0.0001422754,0.00005605402,0.001232791],"study_design_scores_gemma":[0.00001763114,0.0001160892,0.03966533,0.000011116,0.00001172528,0.0009966736,0.0000806036,0.002420228,0.9514905,0.0002061149,0.004969679,0.00001438704],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9936839,0.001168866,0.001587618,0.0001615072,0.00002138263,0.00001976454,0.0005574167,0.0002452526,0.002554247],"genre_scores_gemma":[0.9965839,0.0003976298,0.0008462225,0.00004104288,0.000005695737,0.000009129746,0.0003606038,0.00001833962,0.001737374],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.003618879,"threshold_uncertainty_score":0.007195592,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.009493209842616325,"score_gpt":0.1899961663011984,"score_spread":0.1805029564585821,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}