{"id":"W2100437353","doi":"10.1021/ja500451w","title":"Microarray Discovery of New OGT Substrates: The Medulloblastoma Oncogene OTX2 Is <i>O</i>-GlcNAcylated","year":2014,"lang":"en","type":"article","venue":"Journal of the American Chemical Society","topic":"Glycosylation and Glycoproteins Research","field":"Biochemistry, Genetics and Molecular Biology","cited_by":42,"is_retracted":false,"has_abstract":true,"ca_institutions":"","funders":"National Institute of General Medical Sciences; National Institutes of Health; Simon Fraser University","keywords":"Medulloblastoma; Chemistry; Glycosyltransferase; Serine; Transcription factor; Microarray; Microarray analysis techniques; Computational biology; Cell biology; Biochemistry; Phosphorylation; Gene; Gene expression; Cancer research; Biology","routes":{"ca_aff":false,"ca_fund":true,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":true},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"metacan-v3-hybrid-931329e0061c","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0003058095,0.0005829317,0.0004419542,0.0003682137,0.0003083695,0.0005093951,0.0002709845,0.0004109792,0.0006909608],"category_scores_gemma":[0.000308989,0.0002394208,0.0003124156,0.000437569,0.0001944488,0.000281934,0.0002251944,0.0005556798,0.0004110869],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.0004268751,"about_ca_system_score_gemma":0.0002478486,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.0008014857,"about_ca_topic_score_gemma":0.001651839,"domain_scores_codex":[0.9996787,0.00004650728,0.00001970358,0.0000854679,0.000127758,0.00004189396],"domain_scores_gemma":[0.9998797,0.00003509572,0.00002714518,0.00001355432,0.00002798286,0.00001642634],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","study_design_scores_codex":[0.00002893601,0.000007406843,0.0002022554,0.00001740257,0.00000352733,0.00001368101,0.000006628456,0.00006293632,0.9987367,0.00004501555,0.00003959072,0.0008358527],"study_design_scores_gemma":[0.000004881962,0.00007926601,0.003302276,0.000002649932,0.00001235969,0.00008007571,0.000018404,0.002014249,0.9924225,0.00005537972,0.002001958,0.000006151119],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.8983358,0.002310823,0.09120421,0.00049364,0.0001143619,0.0001711541,0.003023095,0.0008405873,0.003506493],"genre_scores_gemma":[0.8426087,0.003763089,0.137352,0.0003936339,0.00005340206,0.0004763711,0.006878384,0.0001940586,0.008280225],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.0008014857,"threshold_uncertainty_score":0.003097177,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.009210092965607052,"score_gpt":0.2634264915821756,"score_spread":0.2542163986165685,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}