{"id":"W2100517092","doi":"10.1128/aac.01410-07","title":"Daptomycin Exerts Bactericidal Activity without Lysis of <i>Staphylococcus aureus</i>","year":2008,"lang":"en","type":"article","venue":"Antimicrobial Agents and Chemotherapy","topic":"Antimicrobial Resistance in Staphylococcus","field":"Medicine","cited_by":131,"is_retracted":false,"has_abstract":true,"ca_institutions":"University of Guelph","funders":"","keywords":"Daptomycin; Staphylococcus aureus; Lysis; Calcein; Microbiology; Chemistry; Staphylococcus; Cell membrane; Bacterial cell structure; Cell; Bacteria; Biology; Membrane; Vancomycin; Biochemistry","routes":{"ca_aff":true,"ca_fund":false,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"codex-gemma-dda1882f352a","candidate_categories":["metaepi_narrow"],"consensus_categories":[],"category_scores_codex":[0.0001122397,0.0003839048,0.0008423047,0.0001560495,0.0001939245,0.00002082926,0.0001668295,0.0002025066,0.0002748935],"category_scores_gemma":[0.00001761169,0.0003371687,0.0002732006,0.000339018,0.0005006754,0.000150329,0.00006358395,0.0002284298,0.00001409467],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.00005041881,"about_ca_system_score_gemma":0.0001257641,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.0001657739,"about_ca_topic_score_gemma":0.00001325629,"domain_scores_codex":[0.9982441,0.000043677,0.0004302079,0.0005305846,0.0002842172,0.0004672291],"domain_scores_gemma":[0.9988624,0.00003475724,0.0002736537,0.0004760833,0.0001570108,0.0001961024],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","study_design_scores_codex":[0.001224509,0.000604572,0.2124801,0.0001624092,0.0002373847,0.00006699921,0.0005533659,0.000002163793,0.7456654,0.000007427295,0.03467583,0.00431977],"study_design_scores_gemma":[0.004554842,0.0002820081,0.4171457,0.0002223724,0.0001320031,0.0001123307,0.00003306652,0.00004417013,0.5343609,0.000009244096,0.04263151,0.0004718082],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9959922,0.00004608479,0.0004803645,0.001491502,0.0001219594,0.0005289646,0.00005297971,0.00007462895,0.001211327],"genre_scores_gemma":[0.9897633,0.001886477,0.001894909,0.004651343,0.0001540247,0.000007473614,0.00002142331,0.00006897244,0.001552067],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.2113045,"threshold_uncertainty_score":0.999908,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.01806872649864557,"score_gpt":0.2642665838427274,"score_spread":0.2461978573440818,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}