{"id":"W2100548519","doi":"10.2353/jmoldx.2009.090061","title":"Ultrasensitive Detection of KRAS2 Mutations in Bile and Serum from Patients with Biliary Tract Carcinoma Using LigAmp Technology","year":2009,"lang":"en","type":"article","venue":"Journal of Molecular Diagnostics","topic":"Cholangiocarcinoma and Gallbladder Cancer Studies","field":"Medicine","cited_by":10,"is_retracted":false,"has_abstract":false,"ca_institutions":"","funders":"National Cancer Institute; Canadian Institutes of Health Research; Rolfe Pancreatic Cancer Foundation","keywords":"Biliary tract; Biology; Cancer; Carcinoma; Point mutation; Mutation; Adenocarcinoma; Internal medicine; Gastroenterology; Pathology; Medicine; Gene; Genetics","routes":{"ca_aff":false,"ca_fund":true,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":true},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"codex-gemma-dda1882f352a","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.00005552695,0.0001022867,0.0003015245,0.0003229033,0.00002601953,0.00000541288,0.00003025008,0.00007459285,0.000001271618],"category_scores_gemma":[0.0003393399,0.00008267559,0.00005094998,0.0002806305,0.00007268886,0.00005747646,0.000009563107,0.0002112796,1.33299e-7],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.0000642612,"about_ca_system_score_gemma":0.00007607195,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.00003989337,"about_ca_topic_score_gemma":0.00002439877,"domain_scores_codex":[0.9992742,0.0000259366,0.0002947344,0.0001058418,0.0001873391,0.0001119668],"domain_scores_gemma":[0.999182,0.0001449906,0.0002230282,0.00009180199,0.0003027006,0.00005548161],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"observational","study_design_gemma":"observational","study_design_scores_codex":[0.0001445788,0.0003405548,0.9323426,0.0000148454,0.00008006124,0.000633935,0.0004639779,0.0001006955,0.05908537,0.000003036606,0.000004334745,0.006785959],"study_design_scores_gemma":[0.001953935,0.001269411,0.8505734,0.00024748,0.0002872386,0.0001216631,0.0004147042,0.00005620924,0.14484,0.0001645734,0.000003971769,0.00006742819],"study_design_candidate":"observational","study_design_consensus":"observational","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9959928,0.002521954,0.0008697808,0.0003677652,0.00005120927,0.0001589105,0.00002097311,0.000004383749,0.00001219803],"genre_scores_gemma":[0.9983529,0.0001616715,0.001331057,0.0001069471,0.00003302455,7.920244e-7,0.000003814359,0.000009458642,3.524071e-7],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.08575466,"threshold_uncertainty_score":0.3371412,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.006572795304295818,"score_gpt":0.231860674243673,"score_spread":0.2252878789393772,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}