{"id":"W2100582442","doi":"10.1152/ajpregu.00146.2006","title":"Nitric oxide-dependent and -independent mechanisms are involved in TNF-α-induced depression of cardiac myocyte contractility","year":2007,"lang":"en","type":"article","venue":"American Journal of Physiology-Regulatory, Integrative and Comparative Physiology","topic":"Nitric Oxide and Endothelin Effects","field":"Medicine","cited_by":58,"is_retracted":false,"has_abstract":true,"ca_institutions":"Health Sciences Centre","funders":"","keywords":"Contractility; Cardiac myocyte; Nitric oxide; Myocyte; Depression (economics); Internal medicine; Tumor necrosis factor alpha; Cardiology; Medicine; Chemistry; Economics","routes":{"ca_aff":true,"ca_fund":false,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"codex-gemma-dda1882f352a","candidate_categories":["metaepi_narrow"],"consensus_categories":[],"category_scores_codex":[0.0009452605,0.0004487411,0.002380373,0.0005051529,0.00008297426,0.000007171134,0.0001779552,0.00017541,0.0000175802],"category_scores_gemma":[0.0001536295,0.0003101257,0.0002632465,0.0004237447,0.0008592458,0.0001758282,0.0001033123,0.0008932367,0.000002669663],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.0001441405,"about_ca_system_score_gemma":0.0001619572,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.0003010873,"about_ca_topic_score_gemma":0.00008657781,"domain_scores_codex":[0.9968872,0.0007917091,0.00100245,0.0005238614,0.0003300129,0.000464781],"domain_scores_gemma":[0.9962173,0.001061784,0.001549469,0.0003172176,0.0005701695,0.000284105],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"bench_or_experimental","study_design_gemma":"observational","study_design_scores_codex":[0.004849948,0.0004859983,0.01972943,0.00005056697,0.0004569932,0.00001858777,0.0008649525,0.00001796026,0.9694669,0.0003708146,0.00003386224,0.00365403],"study_design_scores_gemma":[0.001561002,0.00168196,0.6652493,0.0001677603,0.0001180731,0.00004281191,0.008377821,0.00005660443,0.3209744,0.001582575,0.00001339076,0.0001742982],"study_design_candidate":"bench_or_experimental","study_design_consensus":null,"genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9975847,0.001349113,0.0003093744,0.00004845945,0.0001569203,0.000432851,0.0000137027,0.00001292615,0.00009196584],"genre_scores_gemma":[0.9986563,0.0002471227,0.0006999992,0.0002161567,0.0001264472,0.00001364294,0.000006331538,0.00001895352,0.00001505067],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.6484925,"threshold_uncertainty_score":0.9999351,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.02185314267781814,"score_gpt":0.2948166901343214,"score_spread":0.2729635474565033,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}