{"id":"W2100648759","doi":"10.3998/ark.5550190.0013.108","title":"Synthesis of heterocyclic compounds based on isatin through 1,3-dipolar cycloaddition reactions","year":2012,"lang":"en","type":"article","venue":"ARKIVOC","topic":"Synthesis and Biological Evaluation","field":"Chemistry","cited_by":145,"is_retracted":false,"has_abstract":true,"ca_institutions":"Université Laval","funders":"","keywords":"Isatin; Chemistry; Cycloaddition; 1,3-Dipolar cycloaddition; Combinatorial chemistry; Organic chemistry; Computational chemistry; Catalysis","routes":{"ca_aff":true,"ca_fund":false,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"codex-gemma-dda1882f352a","candidate_categories":["insufficient_payload"],"consensus_categories":[],"category_scores_codex":[0.0002086838,0.0001300839,0.0001870725,0.00003142657,0.00009512648,0.00001062194,0.0001041751,0.0001391834,0.002527292],"category_scores_gemma":[0.0004902698,0.0001023507,0.0001273863,0.00008207464,0.00006597002,0.0001217696,0.00001521297,0.000104903,0.0001276024],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.00006400898,"about_ca_system_score_gemma":0.000007045422,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.00006546277,"about_ca_topic_score_gemma":0.000002376,"domain_scores_codex":[0.9990175,0.00007885091,0.000282508,0.0001686575,0.000240449,0.0002119786],"domain_scores_gemma":[0.9985273,0.0009107513,0.0001804871,0.0002912541,0.00003576159,0.00005442903],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","study_design_scores_codex":[0.0001045324,0.0009274918,0.01236413,0.00009449628,0.00005141907,4.629381e-7,0.0001031981,0.00005776298,0.9618831,0.0005977383,0.002000595,0.02181504],"study_design_scores_gemma":[0.0001963363,0.00003703662,0.01498029,0.0001461848,0.00005281252,0.000002178914,0.000102052,0.000793569,0.9517856,0.0003475292,0.0313888,0.000167579],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.8754073,0.0001079502,0.0002416186,0.0004127707,0.0001252111,0.0000748752,0.00009107003,0.00009942526,0.1234397],"genre_scores_gemma":[0.9985406,0.00002722679,0.000774989,0.0002252619,0.0002157482,0.00005052901,0.00006618841,0.00001242999,0.00008702142],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.1233527,"threshold_uncertainty_score":0.9983845,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.04804641978259167,"score_gpt":0.2842232967319141,"score_spread":0.2361768769493224,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}