{"id":"W2100653050","doi":"10.1002/stem.1401","title":"FoxG1 Interacts with Bmi1 to Regulate Self-Renewal and Tumorigenicity of Medulloblastoma Stem Cells","year":2013,"lang":"en","type":"article","venue":"Stem Cells","topic":"Glioma Diagnosis and Treatment","field":"Medicine","cited_by":61,"is_retracted":false,"has_abstract":true,"ca_institutions":"Child and Family Research Institute; Hospital for Sick Children; University of British Columbia; BC Children's Hospital; SickKids Foundation; University of Toronto; McMaster University","funders":"Canadian Institutes of Health Research","keywords":"Biology; Medulloblastoma; Wnt signaling pathway; Stem cell; BMI1; Cancer stem cell; Cancer research; Phenotype; Tumor initiation; Gene; Stem cell marker; Genetics; Carcinogenesis","routes":{"ca_aff":true,"ca_fund":true,"ca_venue":false,"about_ca":true,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"metacan-v3-hybrid-931329e0061c","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.00007885013,0.0001671777,0.0001623773,0.0003776369,0.0001362134,0.000204171,0.0001253085,0.00009530671,0.0007817168],"category_scores_gemma":[0.0001185588,0.0001781882,0.0001535205,0.0002105536,0.000162969,0.000103462,0.0002365563,0.0001628511,0.0002746958],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.0004893722,"about_ca_system_score_gemma":0.0002664245,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.00450423,"about_ca_topic_score_gemma":0.01042961,"domain_scores_codex":[0.9999201,0.000005629177,0.000003965406,0.00002152877,0.0000277146,0.00002099231],"domain_scores_gemma":[0.9999437,0.00000921537,0.0000181044,0.000006209214,0.000006110979,0.00001667358],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","study_design_scores_codex":[0.00007606664,0.000005885747,0.003931007,0.00001916793,0.000004958934,0.00002600169,0.00002448029,0.0000900763,0.9942274,0.00008219606,0.00004323203,0.001469546],"study_design_scores_gemma":[0.0000274399,0.0001611965,0.297413,0.00001300284,0.00003619035,0.0002733629,0.0001507414,0.003951539,0.6922366,0.0001803512,0.005546798,0.000009732951],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9965202,0.000942287,0.001024385,0.00003636207,0.0000049652,0.000009471584,0.0005119148,0.00003907538,0.0009113452],"genre_scores_gemma":[0.9951268,0.00051204,0.0009407013,0.0000457067,0.000003343232,0.00001373943,0.001336716,0.0000200478,0.002000896],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.00450423,"threshold_uncertainty_score":0.008956015,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.007434344971964584,"score_gpt":0.2113329840494294,"score_spread":0.2038986390774648,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}