{"id":"W2100703720","doi":"10.1111/j.1399-0004.2011.01780.x","title":"Polycystin-1: a key player in hereditary cystic kidney and liver disorders","year":2011,"lang":"en","type":"letter","venue":"Clinical Genetics","topic":"Genetic and Kidney Cyst Diseases","field":"Biochemistry, Genetics and Molecular Biology","cited_by":0,"is_retracted":false,"has_abstract":true,"ca_institutions":"University of British Columbia","funders":"","keywords":"Polycystic kidney disease; Endoplasmic reticulum; Polycystic kidney; Kidney; Liver disease; Polycystic liver disease; Cyst; Kidney disorder; Biology; Cystic fibrosis; Genetics; Endocrinology; Medicine; Internal medicine; Bioinformatics; Pathology","routes":{"ca_aff":true,"ca_fund":false,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"codex-gemma-dda1882f352a","candidate_categories":["metaepi_narrow","research_integrity"],"consensus_categories":[],"category_scores_codex":[0.0002869538,0.0005545087,0.0006017717,0.00009913962,0.0000595414,0.00003420847,0.0005108989,0.001905863,0.0001326133],"category_scores_gemma":[0.0008300268,0.0005464334,0.0003009852,0.00009284483,0.0005426702,0.000002288509,0.0004505762,0.001061234,0.00009582541],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.00001173275,"about_ca_system_score_gemma":0.000486817,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.00005378249,"about_ca_topic_score_gemma":0.00004865291,"domain_scores_codex":[0.9967026,0.000359685,0.0008934063,0.001141609,0.0002489141,0.0006537552],"domain_scores_gemma":[0.9981909,0.0001343996,0.0002280274,0.0008644992,0.00006822139,0.0005139619],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"not_applicable","study_design_gemma":"not_applicable","study_design_scores_codex":[0.0001370868,0.0001700643,0.01190231,0.0001880496,0.0001328584,0.0002494537,0.00003242601,0.000002868022,0.0002629037,8.090955e-7,0.9843864,0.002534778],"study_design_scores_gemma":[0.001337434,0.00080763,0.01917278,0.000109452,0.0002285386,0.00004540381,0.00001847489,0.0000498485,0.0002310661,0.0003334778,0.9768474,0.0008185674],"study_design_candidate":"not_applicable","study_design_consensus":"not_applicable","genre_codex":"empirical","genre_gemma":"commentary","genre_scores_codex":[0.6296721,0.1256719,0.001692088,0.2030981,0.01256502,0.005111279,0.00505338,0.00022613,0.01691001],"genre_scores_gemma":[0.1370453,0.02471246,0.003966328,0.8137417,0.01077216,0.0001411752,0.004234789,0.0002882486,0.005097844],"genre_candidate":"commentary","genre_consensus":null,"teacher_disagreement_score":0.6106436,"threshold_uncertainty_score":0.9996987,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.02425111129395252,"score_gpt":0.2809639310428216,"score_spread":0.2567128197488691,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}