{"id":"W2100830152","doi":"10.1517/13543784.17.11.1761","title":"Clazosentan: an endothelin receptor antagonist for treatment of vasospasm after subarachnoid hemorrhage","year":2008,"lang":"en","type":"article","venue":"Expert Opinion on Investigational Drugs","topic":"Intracranial Aneurysms: Treatment and Complications","field":"Medicine","cited_by":28,"is_retracted":false,"has_abstract":true,"ca_institutions":"St. Michael's Hospital; University of Toronto","funders":"","keywords":"Subarachnoid hemorrhage; Endothelin receptor antagonist; Vasospasm; Medicine; Cerebral vasospasm; Endothelin receptor; Antagonist; Placebo; Clinical trial; Randomized controlled trial; Receptor antagonist; Anesthesia; Internal medicine; Receptor; Pathology","routes":{"ca_aff":true,"ca_fund":false,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"codex-gemma-dda1882f352a","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.00004533931,0.0002329697,0.0003009806,0.0001104387,0.0002299957,0.00001028243,0.00008178855,0.00009441585,0.0002791209],"category_scores_gemma":[0.00002647653,0.0001921128,0.0001772549,0.0001239562,0.0002527964,0.0001060203,0.000008564194,0.00004784648,0.00009153729],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.0001647884,"about_ca_system_score_gemma":0.0001935344,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.00005882481,"about_ca_topic_score_gemma":0.000001781112,"domain_scores_codex":[0.9987044,0.00003882132,0.0003677265,0.0003684293,0.0003131925,0.0002074176],"domain_scores_gemma":[0.9990489,0.000111583,0.0001145527,0.000345424,0.0001652241,0.0002143345],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","study_design_scores_codex":[0.01752547,0.03272624,0.05576486,0.0005431513,0.0007902537,0.0001774437,0.04263271,0.0001383707,0.5346392,0.215066,0.02323318,0.07676306],"study_design_scores_gemma":[0.01758163,0.01286721,0.04316598,0.0001619943,0.00009093727,0.0006161062,0.001025121,0.005114937,0.7021143,0.004783151,0.2113229,0.001155703],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9831273,0.0008835137,0.0002743491,0.01185713,0.0005435448,0.001393866,0.0004550737,0.0001296389,0.00133557],"genre_scores_gemma":[0.974784,0.0002928804,0.01757148,0.001639543,0.0009751957,0.001034245,0.001803918,0.00004087359,0.001857857],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.2102828,"threshold_uncertainty_score":0.7834135,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.04050734314660269,"score_gpt":0.3031468555725261,"score_spread":0.2626395124259234,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}