{"id":"W2100858113","doi":"10.1056/nejmoa1403086","title":"Simvastatin for the Prevention of Exacerbations in Moderate-to-Severe COPD","year":2014,"lang":"en","type":"article","venue":"New England Journal of Medicine","topic":"Chronic Obstructive Pulmonary Disease (COPD) Research","field":"Medicine","cited_by":347,"is_retracted":false,"has_abstract":true,"ca_institutions":"University of British Columbia; Ottawa Hospital; University of Ottawa","funders":"National Heart, Lung, and Blood Institute; Canadian Institutes of Health Research; University of California, San Francisco; University of Pittsburgh; Medical Center, University of Pittsburgh; National Institutes of Health; National Jewish Health; Ottawa Hospital Research Institute; University of Minnesota; Brigham and Women's Hospital; Temple University; University of Ottawa; U.S. Department of Veterans Affairs","keywords":"Medicine; COPD; Simvastatin; Exacerbation; Randomized controlled trial; Internal medicine; Placebo; Diabetes mellitus; Vital capacity; Physical therapy; Lung; Diffusing capacity","routes":{"ca_aff":true,"ca_fund":true,"ca_venue":false,"about_ca":true,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"metacan-v3-hybrid-931329e0061c","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.001179595,0.0003677094,0.0009775911,0.0002812656,0.0001998025,0.0002972565,0.0002981682,0.0004712514,0.002662149],"category_scores_gemma":[0.001018388,0.00008990976,0.0007530327,0.0003087081,0.0002310194,0.000130599,0.0002622713,0.0006465125,0.0002962298],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.0002713669,"about_ca_system_score_gemma":0.0006914806,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.0004248595,"about_ca_topic_score_gemma":0.001212028,"domain_scores_codex":[0.9996046,0.0001960299,0.00006142781,0.00003034379,0.00005671444,0.00005087691],"domain_scores_gemma":[0.9995458,0.0001238606,0.0001514129,0.00001545677,0.00003541796,0.0001280465],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"design_other","study_design_gemma":"randomized_trial","study_design_scores_codex":[0.4034885,0.008903211,0.1089703,0.01082536,0.005195324,0.0008921305,0.0001737806,0.001109881,0.02993578,0.001425205,0.01189419,0.4171863],"study_design_scores_gemma":[0.3545985,0.14727,0.4316773,0.002121637,0.006816416,0.001756793,0.0001933945,0.002640521,0.008938152,0.001929482,0.04200057,0.00005728991],"study_design_candidate":"randomized_trial","study_design_consensus":null,"genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.8729947,0.115556,0.0008138997,0.003790374,0.0005786555,0.001415742,0.0009332931,0.00009490818,0.003822357],"genre_scores_gemma":[0.9722878,0.0216076,0.001568483,0.001269851,0.0006582002,0.0005942282,0.00065252,0.000005903105,0.001355383],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.002662149,"threshold_uncertainty_score":0.008905768,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.02925928167513992,"score_gpt":0.3299826572713973,"score_spread":0.3007233755962574,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}