{"id":"W2100876843","doi":"10.1096/fj.04-1859fje","title":"Glucocorticoid treatment alleviates dystrophic myofiber pathology by activation of the calcineurin/NF‐AT pathway","year":2004,"lang":"en","type":"article","venue":"The FASEB Journal","topic":"Muscle Physiology and Disorders","field":"Biochemistry, Genetics and Molecular Biology","cited_by":99,"is_retracted":false,"has_abstract":true,"ca_institutions":"Ottawa Hospital; University of Ottawa","funders":"Canadian Institutes of Health Research","keywords":"Deflazacort; Calcineurin; Duchenne muscular dystrophy; Myocyte; Sarcolemma; Phosphatase; Glucocorticoid; Phosphorylation; Signal transduction; Myogenesis; Skeletal muscle; Endocrinology; Dystrophin; Internal medicine; Cell biology; Medicine; Cancer research; Biology; Transplantation","routes":{"ca_aff":true,"ca_fund":true,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"metacan-v3-hybrid-931329e0061c","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.00008527564,0.0004850696,0.0004272745,0.0002766009,0.0001656733,0.0002099357,0.0002938487,0.0002864578,0.0009744996],"category_scores_gemma":[0.00008829467,0.00008596301,0.0002737801,0.0001285563,0.0002604232,0.0001396377,0.0001911056,0.0007413211,0.0001836644],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.0002591293,"about_ca_system_score_gemma":0.0003829779,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.00160264,"about_ca_topic_score_gemma":0.003983952,"domain_scores_codex":[0.9998772,0.0000171127,0.0000148821,0.00002230257,0.00003594552,0.00003247147],"domain_scores_gemma":[0.9999149,0.000006579434,0.00002648515,0.000009297871,0.00001146626,0.000031329],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","study_design_scores_codex":[0.0005472429,0.00009796616,0.0001710743,0.0001570329,0.00001982294,0.00007089741,0.00002204864,0.0000740551,0.992907,0.00006890559,0.0001310035,0.005733028],"study_design_scores_gemma":[0.0003670336,0.004284272,0.01541462,0.00005832842,0.0001287494,0.0006313362,0.0001072062,0.001107415,0.9662311,0.0001488173,0.01149733,0.00002367864],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9844807,0.01065076,0.001498325,0.0003719434,0.0001549973,0.00006384047,0.0005100222,0.0003295577,0.00193972],"genre_scores_gemma":[0.990537,0.004455546,0.001721155,0.0001535684,0.00006871652,0.00006855505,0.0005584398,0.00002481758,0.00241232],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.00160264,"threshold_uncertainty_score":0.003260076,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.00789644552956996,"score_gpt":0.2184341140123753,"score_spread":0.2105376684828054,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}