{"id":"W2100912336","doi":"10.1128/iai.00455-13","title":"Escherichia coli Heat-Stable Toxin b Impairs Intestinal Epithelial Barrier Function by Altering Tight Junction Proteins","year":2013,"lang":"en","type":"article","venue":"Infection and Immunity","topic":"Barrier Structure and Function Studies","field":"Neuroscience","cited_by":75,"is_retracted":false,"has_abstract":true,"ca_institutions":"Université de Montréal","funders":"National Research Centre","keywords":"Biology; Escherichia coli; Tight junction; Escherichia coli Proteins; Microbiology; Toxin; Barrier function; Enterobacteriaceae; Function (biology); Microbial toxins; Bacterial protein; Cell biology; Bacteria; Biochemistry; Genetics; Gene","routes":{"ca_aff":true,"ca_fund":false,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"codex-gemma-dda1882f352a","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0001468011,0.0002232044,0.0001931895,0.0001053365,0.0009945452,0.0001888367,0.00006327936,0.000104277,0.0007868358],"category_scores_gemma":[0.0002905764,0.0001932338,0.00006210078,0.0003423314,0.0001694543,0.0007645161,0.00009692348,0.0004304174,0.0001097605],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.00006682079,"about_ca_system_score_gemma":0.00002957268,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.003203407,"about_ca_topic_score_gemma":0.00005382928,"domain_scores_codex":[0.9987403,0.000216916,0.0002612026,0.0003234531,0.0001712777,0.0002868903],"domain_scores_gemma":[0.9993889,0.00007384238,0.00008426082,0.0002160349,0.0001065816,0.0001303844],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","study_design_scores_codex":[0.00008191973,0.00005577369,0.003532666,0.00002133483,0.00001416588,3.630558e-7,0.0002267677,0.00001141022,0.9867497,0.0001221819,0.002771762,0.006411954],"study_design_scores_gemma":[0.001343325,0.001184822,0.1119871,0.00004513131,0.00005780033,0.0000822131,0.0004808034,0.001507392,0.7751269,0.001342398,0.1062391,0.0006030072],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.981088,0.00008561788,0.01163329,0.0001448101,0.001553071,0.0004895395,0.000009929068,0.0002578147,0.00473787],"genre_scores_gemma":[0.9975128,0.00009025736,0.00006722003,0.0006786427,0.0001663854,0.0001562771,0.000006514209,0.00001941906,0.001302541],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.2116227,"threshold_uncertainty_score":0.86153,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.01545756318614321,"score_gpt":0.2268383659147362,"score_spread":0.211380802728593,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}