{"id":"W2100941174","doi":"10.1002/cyto.10053","title":"Telomere length measurement by fluorescence in situ hybridization and flow cytometry: Tips and pitfalls","year":2002,"lang":"en","type":"article","venue":"Cytometry","topic":"Telomeres, Telomerase, and Senescence","field":"Medicine","cited_by":153,"is_retracted":false,"has_abstract":true,"ca_institutions":"University of British Columbia; BC Cancer Agency","funders":"National Institute of Allergy and Infectious Diseases; National Science Foundation; National Institutes of Health; National Cancer Institute; Bernische Krebsliga; Schweizerischer Nationalfonds zur Förderung der Wissenschaftlichen Forschung","keywords":"Telomere; Fluorescence in situ hybridization; Molecular biology; Flow cytometry; Biology; Peptide nucleic acid; Southern blot; In situ hybridization; DNA; Chemistry; Chromosome; Genetics; Gene; Gene expression","routes":{"ca_aff":true,"ca_fund":false,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"codex-gemma-dda1882f352a","candidate_categories":["metaepi_narrow"],"consensus_categories":[],"category_scores_codex":[0.0005353085,0.000330216,0.0005293904,0.0008057289,0.0001204443,0.00007283422,0.0001305788,0.0001723112,0.0001401599],"category_scores_gemma":[0.0006155591,0.0003122217,0.00004908539,0.001564014,0.0001949361,0.0002630965,0.00008633131,0.0003697217,0.00005839533],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.0001996719,"about_ca_system_score_gemma":0.0000397109,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.00004392814,"about_ca_topic_score_gemma":0.00002094813,"domain_scores_codex":[0.9974769,0.00008166413,0.0004497489,0.000660753,0.0008121159,0.0005188014],"domain_scores_gemma":[0.9988664,0.00009560816,0.0001049639,0.0003987891,0.0001634119,0.0003707662],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"bench_or_experimental","study_design_gemma":"observational","study_design_scores_codex":[0.0001729635,0.0007146365,0.3508034,0.0006270605,0.0001029443,0.0002279497,0.001126224,0.000001638298,0.4108681,0.00005241792,0.01821157,0.2170911],"study_design_scores_gemma":[0.009804344,0.001110005,0.8046924,0.001312214,0.0002590088,0.0009041395,0.001390414,0.005077166,0.15222,0.00007397227,0.021383,0.001773389],"study_design_candidate":"observational","study_design_consensus":null,"genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9826411,0.01350242,0.0006220606,0.0007896172,0.0001596031,0.0005178546,0.00002567399,0.0001300241,0.001611633],"genre_scores_gemma":[0.9934721,0.004045205,0.00151431,0.0004144118,0.0001171259,0.00001739004,0.00002356287,0.00004451943,0.0003513795],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.4538889,"threshold_uncertainty_score":0.999933,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.02527903768353337,"score_gpt":0.2324633552647002,"score_spread":0.2071843175811669,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}