{"id":"W2100953943","doi":"10.1139/v02-078","title":"Synthesis of 1,4-anhydro-<scp>D</scp>-xylitol heteroanalogues of the naturally occurring glycosidase inhibitor salacinol and their evaluation as glycosidase inhibitors","year":2002,"lang":"en","type":"article","venue":"Canadian Journal of Chemistry","topic":"Carbohydrate Chemistry and Synthesis","field":"Chemistry","cited_by":34,"is_retracted":false,"has_abstract":true,"ca_institutions":"Simon Fraser University","funders":"Natural Sciences and Engineering Research Council of Canada; Michael Smith Health Research BC","keywords":"Chemistry; Xylitol; Glycoside hydrolase; Sulfonium; Stereochemistry; Erythritol; Polyol; Enzyme; Biochemistry; Organic chemistry; Salt (chemistry); Fermentation","routes":{"ca_aff":true,"ca_fund":true,"ca_venue":true,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"codex-gemma-dda1882f352a","candidate_categories":["metaepi_narrow"],"consensus_categories":[],"category_scores_codex":[0.0004960435,0.0004019243,0.0006543063,0.0001072238,0.0001754273,0.00007423276,0.0006330876,0.0003846612,0.000536044],"category_scores_gemma":[0.003956949,0.0003176515,0.0004739797,0.0002856985,0.0004663622,0.000218198,0.00006564576,0.0006171044,0.000002097478],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.0003175181,"about_ca_system_score_gemma":0.0006380902,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.000485323,"about_ca_topic_score_gemma":0.0002296618,"domain_scores_codex":[0.9974866,0.00007148406,0.001094203,0.0003242613,0.0005653536,0.0004580792],"domain_scores_gemma":[0.9962701,0.0007384102,0.001187538,0.0005853824,0.0005647,0.0006538197],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","study_design_scores_codex":[0.00001600011,0.00005381976,0.003141396,0.0006262233,0.0002023683,0.00004255544,0.001023602,0.00005165387,0.9907183,0.000001690507,0.0007989845,0.003323422],"study_design_scores_gemma":[0.0005075368,0.00001646916,0.0001099709,0.001163722,0.0002002468,0.0004375052,0.002041819,0.000353872,0.9939687,0.0001179909,0.0009172788,0.0001648573],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9873009,0.003364583,6.300391e-7,0.0001334345,0.0001539161,0.00008462473,0.0001905339,0.00001061965,0.008760757],"genre_scores_gemma":[0.9992157,0.00005148882,0.00001905026,0.00003928893,0.0003775121,0.000009817519,0.000006454188,0.00003963602,0.0002411192],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.01191473,"threshold_uncertainty_score":0.9999276,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.0127169217626822,"score_gpt":0.200099078185128,"score_spread":0.1873821564224458,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}