{"id":"W2100996803","doi":"10.2337/db09-1886","title":"In Vivo Expression of HGF/NK1 and GLP-1 From dsAAV Vectors Enhances Pancreatic β-Cell Proliferation and Improves Pathology in the <i>db/db</i> Mouse Model of Diabetes","year":2010,"lang":"en","type":"article","venue":"Diabetes","topic":"Pancreatic function and diabetes","field":"Medicine","cited_by":37,"is_retracted":false,"has_abstract":true,"ca_institutions":"University of British Columbia","funders":"Fondation pour la Recherche Médicale; University of Pittsburgh; Michael Smith Health Research BC; Stem Cell Network; Canadian Diabetes Association","keywords":"In vivo; Islet; Hepatocyte growth factor; Pancreatic islets; Cell growth; Endocrinology; Biology; Internal medicine; In vitro; Insulin; Cell biology; Medicine; Receptor","routes":{"ca_aff":true,"ca_fund":true,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"metacan-v3-hybrid-931329e0061c","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0003023469,0.0008014548,0.0004352767,0.000468844,0.0001731777,0.0005221153,0.0003299296,0.0004849434,0.001758929],"category_scores_gemma":[0.0001138836,0.0002546578,0.0004678596,0.0001713407,0.0003958515,0.0004131139,0.000217409,0.001311943,0.0004424955],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.0003691889,"about_ca_system_score_gemma":0.0002674571,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.0004529477,"about_ca_topic_score_gemma":0.0005468451,"domain_scores_codex":[0.9996661,0.00004323629,0.00005825997,0.00007952842,0.00007832263,0.00007454905],"domain_scores_gemma":[0.9997153,0.00002200292,0.0001138224,0.0000172479,0.00001842617,0.000113199],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","study_design_scores_codex":[0.0002117686,0.00008192338,0.00009566084,0.00003668809,0.000005415706,0.0000205267,0.000008748983,0.0000260439,0.9988992,0.00005155335,0.000023784,0.0005386819],"study_design_scores_gemma":[0.00006675973,0.0008914073,0.001403444,0.00001042688,0.00002904758,0.000252025,0.00002822553,0.000349884,0.9955875,0.00002218445,0.001354396,0.000004557728],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9917998,0.001329078,0.004179623,0.0001907284,0.00009222978,0.00006879462,0.0005396761,0.0002014968,0.001598487],"genre_scores_gemma":[0.9799407,0.001995548,0.009277908,0.0002130664,0.00005714433,0.0001781901,0.001640305,0.0001443044,0.006552948],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.001758929,"threshold_uncertainty_score":0.00588423,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.007124461924339867,"score_gpt":0.2183491475041731,"score_spread":0.2112246855798332,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}