{"id":"W2100996803","doi":"10.2337/db09-1886","title":"In Vivo Expression of HGF/NK1 and GLP-1 From dsAAV Vectors Enhances Pancreatic β-Cell Proliferation and Improves Pathology in the <i>db/db</i> Mouse Model of Diabetes","year":2010,"lang":"en","type":"article","venue":"Diabetes","topic":"Pancreatic function and diabetes","field":"Medicine","cited_by":37,"is_retracted":false,"has_abstract":true,"ca_institutions":"University of British Columbia","funders":"Fondation pour la Recherche Médicale; University of Pittsburgh; Michael Smith Health Research BC; Stem Cell Network; Canadian Diabetes Association","keywords":"In vivo; Islet; Hepatocyte growth factor; Pancreatic islets; Cell growth; Endocrinology; Biology; Internal medicine; In vitro; Insulin; Cell biology; Medicine; Receptor","routes":{"ca_aff":true,"ca_fund":true,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"codex-gemma-dda1882f352a","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.000390186,0.0001858175,0.0005353107,0.0001668449,0.00003861732,0.00001990056,0.0000849652,0.0001584183,0.0000306959],"category_scores_gemma":[0.0004171068,0.0001259346,0.0000406901,0.0001446654,0.0002711732,0.0001741292,0.00004170211,0.000223293,8.05825e-7],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.000007861851,"about_ca_system_score_gemma":0.00004774965,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.00005757263,"about_ca_topic_score_gemma":0.00002465218,"domain_scores_codex":[0.9987499,0.0001120661,0.0004189919,0.0002889629,0.0001844021,0.0002457496],"domain_scores_gemma":[0.9988171,0.0006070692,0.0001779094,0.0002765623,0.00005349462,0.00006781263],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","study_design_scores_codex":[0.00002452166,0.0001472838,0.3069174,0.0001680427,0.0000071055,3.952465e-7,0.001130423,0.00000320663,0.6913084,0.00002537881,0.00005164752,0.0002162055],"study_design_scores_gemma":[0.001385018,0.0002451902,0.02916149,0.0001354327,0.00006264949,1.932655e-7,0.0002942953,0.006029935,0.9616097,0.0009472516,0.00001639569,0.0001124957],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9980674,0.0009082536,0.000006523661,0.0001710725,0.00007693118,0.0004346919,0.00005114648,0.00001511797,0.0002688992],"genre_scores_gemma":[0.9984099,0.0001206591,0.0008222998,0.0003769758,0.00005092382,0.00009991955,0.00002023902,0.00001598233,0.00008309181],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.2777559,"threshold_uncertainty_score":0.5135463,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.007124461924339867,"score_gpt":0.2183491475041731,"score_spread":0.2112246855798332,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}