{"id":"W2101002731","doi":"10.1371/journal.pone.0010347","title":"Isoform-Specific Upregulation of Palladin in Human and Murine Pancreas Tumors","year":2010,"lang":"en","type":"article","venue":"PLoS ONE","topic":"Pancreatic and Hepatic Oncology Research","field":"Medicine","cited_by":53,"is_retracted":false,"has_abstract":true,"ca_institutions":"University of Toronto","funders":"Fox Chase Cancer Center; National Institute of Diabetes and Digestive and Kidney Diseases; National Center for Research Resources; National Institute of General Medical Sciences; Pancreatic Cancer Action Network; Canadian Institutes of Health Research; Gillings School of Public Health; Center for Gastrointestinal Biology and Disease, School of Medicine, University of North Carolina at Chapel Hill; National Cancer Institute; University of North Carolina at Chapel Hill; National Institutes of Health; Barts and The London School of Medicine and Dentistry","keywords":"Downregulation and upregulation; Gene isoform; Pancreas; Cell biology; Biology; Biochemistry; Gene","routes":{"ca_aff":true,"ca_fund":true,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"codex-gemma-dda1882f352a","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0003079923,0.00007426004,0.000399403,0.0001456202,0.00003249272,0.000004098524,0.00004635667,0.00008999599,0.0005181884],"category_scores_gemma":[0.0001241183,0.00006463582,0.00001957883,0.0001225703,0.0001573905,0.00004088259,0.00003204479,0.0002521903,0.00001099421],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.00002338719,"about_ca_system_score_gemma":0.00004468335,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.0001093306,"about_ca_topic_score_gemma":0.0001377965,"domain_scores_codex":[0.9991614,0.00002643204,0.0002506108,0.0001464939,0.0002382085,0.0001768698],"domain_scores_gemma":[0.9994696,0.00008688533,0.00005604971,0.0002119473,0.00007571857,0.00009975066],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"observational","study_design_gemma":"observational","study_design_scores_codex":[0.00009030983,0.0006617249,0.6429719,0.0001249099,0.00003977702,0.00001075928,0.0001728169,4.391081e-8,0.354307,0.001212136,0.0000296657,0.000378995],"study_design_scores_gemma":[0.001651512,0.0003378051,0.971526,0.0002199892,0.00005977313,0.00001005617,0.00004514924,0.000343226,0.02495833,0.0007414552,0.00004859381,0.00005810127],"study_design_candidate":"observational","study_design_consensus":"observational","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9914532,0.0001125141,0.00000533082,0.0003180169,0.000008317541,0.0003629714,0.000002690221,0.00001590302,0.007721038],"genre_scores_gemma":[0.9962137,0.0001019907,0.00244714,0.00002143216,0.00008836626,0.00002226584,0.0000176478,0.00001071062,0.001076738],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.3293487,"threshold_uncertainty_score":0.56738,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.05852594828487408,"score_gpt":0.3035813467278952,"score_spread":0.2450553984430211,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}