{"id":"W2101009063","doi":"10.1158/0008-5472.can-07-0478","title":"Androgen-Induced Wnt Signaling in Preosteoblasts Promotes the Growth of MDA-PCa-2b Human Prostate Cancer Cells","year":2007,"lang":"en","type":"article","venue":"Cancer Research","topic":"Prostate Cancer Treatment and Research","field":"Medicine","cited_by":39,"is_retracted":false,"has_abstract":true,"ca_institutions":"Immunovaccine (Canada)","funders":"T.J. Martell Foundation; U.S. Department of Defense","keywords":"Dihydrotestosterone; Wnt signaling pathway; Androgen receptor; Prostate cancer; Cell growth; Endocrinology; Paracrine signalling; Androgen; Chemistry; Internal medicine; Cancer research; Signal transduction; Biology; Cell biology; Receptor; Cancer; Medicine; Hormone; Biochemistry","routes":{"ca_aff":true,"ca_fund":false,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"metacan-v3-hybrid-931329e0061c","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0001616927,0.0004395451,0.0004111602,0.0004960922,0.0002787428,0.0004008959,0.0001705529,0.0002290125,0.002616611],"category_scores_gemma":[0.00009353516,0.000290626,0.0006647548,0.0006026811,0.0001480152,0.0001695014,0.0001947916,0.0008068905,0.001311461],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.0004072471,"about_ca_system_score_gemma":0.0005733378,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.009308496,"about_ca_topic_score_gemma":0.01686128,"domain_scores_codex":[0.9997812,0.00002848438,0.00002145102,0.0000327993,0.00008446335,0.00005160059],"domain_scores_gemma":[0.9999287,0.00001241943,0.000007972372,0.00001028306,0.00001674387,0.0000239499],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","study_design_scores_codex":[0.0001789478,0.0001034313,0.0004996185,0.00009113404,0.00001224311,0.0001167992,0.00006951346,0.00007209482,0.9968367,0.0001475573,0.0003361339,0.001535785],"study_design_scores_gemma":[0.00007396766,0.0008429045,0.03470472,0.0000236777,0.00005956616,0.0007553651,0.0001518796,0.001910029,0.9433465,0.00008967269,0.01802447,0.0000172025],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9711093,0.01194669,0.004216879,0.0005055068,0.0001234768,0.000141764,0.005114053,0.0002936153,0.00654877],"genre_scores_gemma":[0.9650548,0.006745872,0.004834921,0.000233155,0.00003989169,0.00021729,0.007918584,0.00005229027,0.01490315],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.009308496,"threshold_uncertainty_score":0.01850861,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.09344612595770783,"score_gpt":0.4287663579007316,"score_spread":0.3353202319430237,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}