{"id":"W2101020904","doi":"10.1186/s13578-015-0035-9","title":"Exogenous hydrogen sulfide restores cardioprotection of ischemic post-conditioning via inhibition of mPTP opening in the aging cardiomyocytes","year":2015,"lang":"en","type":"article","venue":"Cell & Bioscience","topic":"Sulfur Compounds in Biology","field":"Biochemistry, Genetics and Molecular Biology","cited_by":39,"is_retracted":false,"has_abstract":true,"ca_institutions":"Lakehead University","funders":"National Natural Science Foundation of China","keywords":"Cardioprotection; Protein kinase B; PI3K/AKT/mTOR pathway; Cell biology; Chemistry; Apoptosis; Cytochrome c; Pharmacology; Biology; Ischemia; Biochemistry; Internal medicine; Medicine","routes":{"ca_aff":true,"ca_fund":false,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"metacan-v3-hybrid-931329e0061c","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0001303985,0.0004038787,0.0003466551,0.0001592404,0.0001200164,0.000143624,0.0001723374,0.0002101612,0.000823534],"category_scores_gemma":[0.00009914752,0.00009469242,0.0002779453,0.00009614934,0.0001966516,0.00026028,0.0001990134,0.0004489914,0.0001055104],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.0001087808,"about_ca_system_score_gemma":0.0002213805,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.0004639288,"about_ca_topic_score_gemma":0.000726815,"domain_scores_codex":[0.9999543,0.000007502675,0.000008104253,0.000009621514,0.0000096743,0.00001078762],"domain_scores_gemma":[0.9999303,0.000005968848,0.00002054604,0.000008925752,0.0000111126,0.00002328703],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","study_design_scores_codex":[0.0009010821,0.0001060684,0.0002329544,0.0001273601,0.00001998654,0.0001012272,0.00002449692,0.0000615994,0.9951482,0.00005074238,0.00005849019,0.003167781],"study_design_scores_gemma":[0.0001286955,0.002465585,0.008840867,0.00001616833,0.00008640414,0.000202195,0.00005671317,0.0006330995,0.9857234,0.00008929573,0.001748422,0.0000091545],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.994158,0.003373823,0.001560164,0.0001072154,0.00006509855,0.00002601732,0.0001274717,0.00008344436,0.0004987732],"genre_scores_gemma":[0.996242,0.001517534,0.0009941942,0.00008131632,0.00003043754,0.00002503046,0.0002169287,0.00001274579,0.0008797469],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.000823534,"threshold_uncertainty_score":0.002754986,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.01627602679692169,"score_gpt":0.2442654763792607,"score_spread":0.227989449582339,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}