{"id":"W2101026420","doi":"10.1091/mbc.e07-01-0047","title":"Dystroglycan and Protein<i>O</i>-Mannosyltransferases 1 and 2 Are Required to Maintain Integrity of<i>Drosophila</i>Larval Muscles","year":2007,"lang":"en","type":"article","venue":"Molecular Biology of the Cell","topic":"Muscle Physiology and Disorders","field":"Biochemistry, Genetics and Molecular Biology","cited_by":62,"is_retracted":false,"has_abstract":true,"ca_institutions":"University of Toronto","funders":"Natural Sciences and Engineering Research Council of Canada; University of Washington; Lunds Universitet; Canada Research Chairs; Mizutani Foundation for Glycoscience; Florida State University","keywords":"Biology; Dystroglycan; Gene knockdown; Mutant; Cell biology; Muscular dystrophy; Glycosylation; RNA interference; Drosophila melanogaster; Gene; Genetics; Laminin; RNA; Extracellular matrix","routes":{"ca_aff":true,"ca_fund":true,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"metacan-v3-hybrid-931329e0061c","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.00006444202,0.0004421936,0.0001624939,0.000199422,0.000238051,0.0002958925,0.0001742806,0.0003291307,0.0008318222],"category_scores_gemma":[0.0001026015,0.0001730006,0.0001565411,0.0001088325,0.0003296212,0.0002411691,0.0002589792,0.000306705,0.000272763],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.0004103661,"about_ca_system_score_gemma":0.0002622713,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.0011935,"about_ca_topic_score_gemma":0.002782288,"domain_scores_codex":[0.999915,0.000007477729,0.000006000513,0.00002617322,0.00002655035,0.00001873903],"domain_scores_gemma":[0.9998823,0.000008492426,0.00006717264,0.000006146712,0.000008618171,0.00002723201],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","study_design_scores_codex":[0.00004035949,0.000004061663,0.0004525313,0.00001870492,0.000002032421,0.000062967,0.000006411214,0.00003267495,0.998493,0.0001893912,0.00003033011,0.0006675693],"study_design_scores_gemma":[0.00001301939,0.0001190507,0.03407724,0.000008924189,0.00001791213,0.0007354576,0.00004909245,0.0006883277,0.9597026,0.0001505561,0.004431203,0.00000661067],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9938444,0.00173382,0.001864765,0.00009651243,0.00001553396,0.0000147863,0.0002395307,0.00004018991,0.002150574],"genre_scores_gemma":[0.9912918,0.001116444,0.003428205,0.00007336184,0.000007606039,0.00001710703,0.0004888467,0.00001613182,0.003560527],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.0011935,"threshold_uncertainty_score":0.002977431,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.006460072544384104,"score_gpt":0.240056659195714,"score_spread":0.2335965866513299,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}