{"id":"W2101043191","doi":"10.1128/jvi.05705-11","title":"2009 Pandemic H1N1 Influenza Virus Causes Disease and Upregulation of Genes Related to Inflammatory and Immune Responses, Cell Death, and Lipid Metabolism in Pigs","year":2011,"lang":"en","type":"article","venue":"Journal of Virology","topic":"Influenza Virus Research Studies","field":"Medicine","cited_by":67,"is_retracted":false,"has_abstract":true,"ca_institutions":"","funders":"National Institute of Allergy and Infectious Diseases; National Center for Research Resources; U.S. Public Health Service; National Institutes of Health; U.S. Department of Health and Human Services","keywords":"Biology; Virus; Virology; Immune system; Pandemic; Virulence; Downregulation and upregulation; Influenza A virus; Gene; Innate immune system; Pathogenesis; Immunology; Microbiology; Disease; Infectious disease (medical specialty); Medicine; Genetics; Coronavirus disease 2019 (COVID-19)","routes":{"ca_aff":false,"ca_fund":false,"ca_venue":false,"about_ca":true,"invisible_to_affiliation_only":true},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"metacan-v3-hybrid-931329e0061c","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0001671968,0.0004212556,0.0003218956,0.0003375822,0.0002287292,0.0002877166,0.00009578485,0.0005749338,0.0008770805],"category_scores_gemma":[0.00009767199,0.00021578,0.0005242839,0.0001795858,0.0002982333,0.0002176438,0.0002316339,0.0005299241,0.0002417624],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.0002728475,"about_ca_system_score_gemma":0.0002243158,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.001051044,"about_ca_topic_score_gemma":0.001525099,"domain_scores_codex":[0.9998017,0.00002905966,0.00001332851,0.00006116294,0.00002861367,0.00006616097],"domain_scores_gemma":[0.9999084,0.00001709213,0.00002834224,0.00001034681,0.00001131588,0.0000244236],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","study_design_scores_codex":[0.0004033522,0.00008058884,0.007593558,0.00005135932,0.00002137765,0.0001318421,0.000052669,0.00006306763,0.9901016,0.00002836634,0.00005996083,0.001412327],"study_design_scores_gemma":[0.00005569602,0.002978163,0.7942106,0.00002413139,0.00008191182,0.001412598,0.0005286794,0.001320208,0.1975688,0.000193579,0.001594698,0.00003092014],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9977963,0.0004357145,0.0003740069,0.00005160661,0.00001947383,0.00001917326,0.0004423614,0.00001207849,0.0008492517],"genre_scores_gemma":[0.9950495,0.0005772593,0.001078673,0.0002011445,0.00002296876,0.00008265439,0.001346187,0.000009629308,0.001631928],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.001051044,"threshold_uncertainty_score":0.002934158,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.05755238840207216,"score_gpt":0.3383497839354742,"score_spread":0.280797395533402,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}