{"id":"W2101043191","doi":"10.1128/jvi.05705-11","title":"2009 Pandemic H1N1 Influenza Virus Causes Disease and Upregulation of Genes Related to Inflammatory and Immune Responses, Cell Death, and Lipid Metabolism in Pigs","year":2011,"lang":"en","type":"article","venue":"Journal of Virology","topic":"Influenza Virus Research Studies","field":"Medicine","cited_by":67,"is_retracted":false,"has_abstract":true,"ca_institutions":"","funders":"National Institute of Allergy and Infectious Diseases; National Center for Research Resources; U.S. Public Health Service; National Institutes of Health; U.S. Department of Health and Human Services","keywords":"Biology; Virus; Virology; Immune system; Pandemic; Virulence; Downregulation and upregulation; Influenza A virus; Gene; Innate immune system; Pathogenesis; Immunology; Microbiology; Disease; Infectious disease (medical specialty); Medicine; Genetics; Coronavirus disease 2019 (COVID-19)","routes":{"ca_aff":false,"ca_fund":false,"ca_venue":false,"about_ca":true,"invisible_to_affiliation_only":true},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"codex-gemma-dda1882f352a","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0008830414,0.0001556764,0.0005672079,0.0005976325,0.00005162812,0.000006477135,0.00006661694,0.0001361301,0.00002394093],"category_scores_gemma":[0.0006849444,0.0001239868,0.00004562399,0.0001292296,0.0002614413,0.0001744742,0.0001338298,0.0003217315,0.000001719646],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.00003183145,"about_ca_system_score_gemma":0.0001374994,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.0001045733,"about_ca_topic_score_gemma":0.0000355193,"domain_scores_codex":[0.9983617,0.0002786389,0.0007444237,0.0001644528,0.0002087566,0.0002420392],"domain_scores_gemma":[0.9988398,0.0002219341,0.0003227888,0.0001600641,0.000201424,0.0002539881],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"observational","study_design_gemma":"observational","study_design_scores_codex":[0.008392486,0.0000829846,0.6278198,0.00009697367,0.0001333172,0.0001373228,0.001827712,0.00001533169,0.3601817,0.00008281845,0.00001785255,0.001211748],"study_design_scores_gemma":[0.003110199,0.0006172134,0.9879032,0.00009140626,0.0001977877,0.0001540958,0.00009147744,0.00002778991,0.006178511,0.0005215673,0.001012216,0.00009451213],"study_design_candidate":"observational","study_design_consensus":"observational","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9567455,0.04275273,0.00000574195,0.0001354008,0.00005380341,0.0002450706,0.0000106698,0.000006755502,0.00004434961],"genre_scores_gemma":[0.9909534,0.008214469,0.0004031875,0.0003051053,0.00004965535,0.000006318054,6.850298e-7,0.00001598414,0.00005116762],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.3600834,"threshold_uncertainty_score":0.5056035,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.05755238840207216,"score_gpt":0.3383497839354742,"score_spread":0.280797395533402,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}