{"id":"W2101063971","doi":"10.1074/jbc.m600804200","title":"Characterization of the GbpD-activated Rap1 Pathway Regulating Adhesion and Cell Polarity in Dictyostelium discoideum","year":2006,"lang":"en","type":"article","venue":"Journal of Biological Chemistry","topic":"Cellular Mechanics and Interactions","field":"Biochemistry, Genetics and Molecular Biology","cited_by":56,"is_retracted":false,"has_abstract":true,"ca_institutions":"University of British Columbia","funders":"Canadian Institutes of Health Research; Max-Planck-Gesellschaft; Nederlandse Organisatie voor Wetenschappelijk Onderzoek","keywords":"Dictyostelium discoideum; Cell biology; Polarity (international relations); Rap1; Adhesion; Dictyostelium; Cell adhesion; Characterization (materials science); Cell polarity; Chemistry; Cell; Signal transduction; Biology; Nanotechnology; Biochemistry; Materials science; Gene","routes":{"ca_aff":true,"ca_fund":true,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"codex-gemma-dda1882f352a","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.000171108,0.00008793987,0.0001410256,0.0000139869,0.00003876078,0.00001092552,0.0001095036,0.0001658468,0.00001646788],"category_scores_gemma":[0.0000752983,0.00005525112,0.00009223943,0.00007130585,0.00004416668,0.00000648178,0.00008415266,0.0001737566,9.656073e-8],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.00001467744,"about_ca_system_score_gemma":0.00003141351,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.00001119751,"about_ca_topic_score_gemma":0.000002150671,"domain_scores_codex":[0.9993004,0.0000473449,0.000355757,0.0001176936,0.00008020933,0.00009856644],"domain_scores_gemma":[0.9993871,0.00001368664,0.0003846083,0.000113435,0.00007134338,0.00002982211],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","study_design_scores_codex":[0.00006267875,0.0000986897,0.007691802,0.00001541461,0.000004819271,0.000001319769,0.000006045553,0.000003558631,0.9919484,0.000006583882,0.00000737676,0.0001533446],"study_design_scores_gemma":[0.0002823868,0.00009047458,0.02842753,0.00003841701,0.000004677055,0.00003302078,0.00003370659,0.00002723418,0.9701349,0.00007664461,0.0007868824,0.00006416099],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9992144,0.0001770514,0.0001258286,0.0001015526,0.00006695545,0.00004573629,0.000013562,0.000001425573,0.0002535525],"genre_scores_gemma":[0.9995165,0.00008878359,0.0000587584,0.00002279011,0.0001396486,8.104017e-7,0.00004407093,0.000005202809,0.0001234085],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.0218135,"threshold_uncertainty_score":0.2253075,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.008924653817435214,"score_gpt":0.2066784785437079,"score_spread":0.1977538247262727,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}