{"id":"W2101082817","doi":"10.1158/0008-5472.can-05-0729","title":"Evidence for the Direct Binding of Phosphorylated p53 to Sites of DNA Breaks <i>In vivo</i>","year":2005,"lang":"en","type":"article","venue":"Cancer Research","topic":"DNA Repair Mechanisms","field":"Biochemistry, Genetics and Molecular Biology","cited_by":108,"is_retracted":false,"has_abstract":true,"ca_institutions":"University of Toronto; Hospital for Sick Children; Princess Margaret Cancer Centre; University Health Network","funders":"","keywords":"DNA damage; Chromatin; Biology; G2-M DNA damage checkpoint; DNA; DNA repair; Molecular biology; Cell biology; Cell cycle; Phosphorylation; Carcinogenesis; Genome instability; Histone; Cell cycle checkpoint; Cell; Biochemistry; Gene","routes":{"ca_aff":true,"ca_fund":false,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"metacan-v3-hybrid-931329e0061c","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0001397429,0.0003820139,0.0001194934,0.0002598237,0.0001912963,0.0002197725,0.0002062411,0.0002529033,0.003161035],"category_scores_gemma":[0.0001530414,0.0001633996,0.0002247155,0.0001235883,0.0002372724,0.0001452292,0.0002027427,0.000320694,0.0007462768],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.0001955175,"about_ca_system_score_gemma":0.0001059462,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.0004100609,"about_ca_topic_score_gemma":0.0005156349,"domain_scores_codex":[0.9999136,0.00001055663,0.000006453571,0.00002947322,0.00002299244,0.00001698199],"domain_scores_gemma":[0.9998465,0.00002962838,0.00004382116,0.00002431036,0.00002129057,0.00003437123],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","study_design_scores_codex":[0.00007338264,0.000009362623,0.0004026513,0.00004525006,0.000004671667,0.0000986039,0.000008605862,0.00001392454,0.9985305,0.00005977396,0.0000292996,0.0007241074],"study_design_scores_gemma":[0.000005783399,0.0002288765,0.01771996,0.000006668247,0.00001073667,0.001015198,0.000016955,0.0002538003,0.9792576,0.00006499601,0.001416574,0.000002835205],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9813786,0.005126301,0.009183631,0.0001912207,0.00005987197,0.00003513541,0.0005473318,0.0001394783,0.003338461],"genre_scores_gemma":[0.9910705,0.001697153,0.003689692,0.00007059615,0.00003330854,0.0000284672,0.0009889521,0.00001748009,0.00240387],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.003161035,"threshold_uncertainty_score":0.01057476,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.09208331176881217,"score_gpt":0.4058169437503644,"score_spread":0.3137336319815522,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}