{"id":"W2101083042","doi":"10.1158/1055-9965.epi-08-0926","title":"Global DNA Hypomethylation (LINE-1) in the Normal Colon and Lifestyle Characteristics and Dietary and Genetic Factors","year":2009,"lang":"en","type":"article","venue":"Cancer Epidemiology Biomarkers & Prevention","topic":"Epigenetics and DNA Methylation","field":"Biochemistry, Genetics and Molecular Biology","cited_by":146,"is_retracted":false,"has_abstract":true,"ca_institutions":"University of Toronto","funders":"National Cancer Institute; National Institutes of Health","keywords":"DNA methylation; Genetics; Line (geometry); DNA; Biology; Gene; Gene expression; Mathematics","routes":{"ca_aff":true,"ca_fund":false,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"metacan-v3-hybrid-931329e0061c","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0003632561,0.0001888135,0.0002602733,0.0003581497,0.0001402134,0.0001966823,0.0001066035,0.0002251234,0.001408036],"category_scores_gemma":[0.001102518,0.0001349192,0.0001426667,0.0002975074,0.0002086834,0.0001078583,0.0001291716,0.0002101635,0.0001319197],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.0001217571,"about_ca_system_score_gemma":0.00009676681,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.001294605,"about_ca_topic_score_gemma":0.001760386,"domain_scores_codex":[0.9997796,0.00007596237,0.00001232254,0.00007550676,0.00003272261,0.00002390713],"domain_scores_gemma":[0.9991627,0.0001985458,0.0003842177,0.00007790737,0.00006170779,0.0001149689],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"observational","study_design_gemma":"observational","study_design_scores_codex":[0.002412701,0.00005571771,0.9827885,0.00002804499,0.0001502898,0.00008698597,0.00005845963,0.00007047228,0.01031474,0.000009776072,0.00004594584,0.003978431],"study_design_scores_gemma":[0.000008980422,0.0003144633,0.9987798,0.000001971336,0.00003048192,0.0002648392,0.00001550454,0.00008106294,0.0004239396,0.000009882187,0.00006801167,0.000001141912],"study_design_candidate":"observational","study_design_consensus":"observational","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9993624,0.0002680941,0.0001205676,0.00001013465,0.000001103697,0.000004600974,0.0001105074,0.000003218995,0.0001194103],"genre_scores_gemma":[0.99961,0.00004453893,0.0001172961,0.000007165891,0.000002257055,0.000003982721,0.0001170916,0.000001458108,0.00009619757],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.001408036,"threshold_uncertainty_score":0.004710376,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.03142614354151036,"score_gpt":0.3335783087140117,"score_spread":0.3021521651725013,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}