{"id":"W2101093259","doi":"10.1128/aem.03065-05","title":"The Cell Lysis Activity of the <i>Streptococcus agalactiae</i> Bacteriophage B30 Endolysin Relies on the Cysteine, Histidine-Dependent Amidohydrolase/Peptidase Domain","year":2006,"lang":"en","type":"article","venue":"Applied and Environmental Microbiology","topic":"Bacteriophages and microbial interactions","field":"Environmental Science","cited_by":68,"is_retracted":false,"has_abstract":true,"ca_institutions":"Université Laval","funders":"National Institute of Allergy and Infectious Diseases; Natural Sciences and Engineering Research Council of Canada; U.S. Department of Agriculture","keywords":"Lysin; Amidohydrolase; Lysis; Bacteriophage; Biochemistry; Lytic cycle; Cysteine; Biology; Histidine; Microbiology; Chemistry; Enzyme; Escherichia coli; Virology; Gene","routes":{"ca_aff":true,"ca_fund":true,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"metacan-v3-hybrid-931329e0061c","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0001489346,0.0002834469,0.0002316467,0.0001410991,0.0001185025,0.0003618035,0.00008282752,0.0001831939,0.0006930921],"category_scores_gemma":[0.0002386375,0.00008989947,0.0002323547,0.0001090278,0.0002088144,0.0001327805,0.0002443215,0.0002817841,0.0006184009],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.00026005,"about_ca_system_score_gemma":0.0002882979,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.001031186,"about_ca_topic_score_gemma":0.000802862,"domain_scores_codex":[0.9998117,0.00002664007,0.00001734227,0.00002275111,0.00006906391,0.00005257218],"domain_scores_gemma":[0.9998164,0.00004063532,0.00003363461,0.000020784,0.00003994742,0.00004867592],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","study_design_scores_codex":[0.00004313674,0.0000113985,0.0004350126,0.00001608763,0.000002851484,0.00002168204,0.00001133956,0.00002605149,0.9983188,0.00006058042,0.00002138446,0.001031755],"study_design_scores_gemma":[0.000005408884,0.0001222278,0.00702988,0.000004951282,0.000004027007,0.000192586,0.00001898346,0.0004177002,0.9911987,0.00004282525,0.0009590525,0.000003535119],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.994919,0.0008316668,0.002274932,0.0000520511,0.00001133261,0.00001633273,0.000206211,0.00006052314,0.001627835],"genre_scores_gemma":[0.9963791,0.000234638,0.00138102,0.0000189702,0.00000323308,0.000009942104,0.0005101341,0.00001243345,0.001450515],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.001031186,"threshold_uncertainty_score":0.002318621,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.001954402275879309,"score_gpt":0.1453802548217061,"score_spread":0.1434258525458268,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}