{"id":"W2101093259","doi":"10.1128/aem.03065-05","title":"The Cell Lysis Activity of the <i>Streptococcus agalactiae</i> Bacteriophage B30 Endolysin Relies on the Cysteine, Histidine-Dependent Amidohydrolase/Peptidase Domain","year":2006,"lang":"en","type":"article","venue":"Applied and Environmental Microbiology","topic":"Bacteriophages and microbial interactions","field":"Environmental Science","cited_by":68,"is_retracted":false,"has_abstract":true,"ca_institutions":"Université Laval","funders":"National Institute of Allergy and Infectious Diseases; Natural Sciences and Engineering Research Council of Canada; U.S. Department of Agriculture","keywords":"Lysin; Amidohydrolase; Lysis; Bacteriophage; Biochemistry; Lytic cycle; Cysteine; Biology; Histidine; Microbiology; Chemistry; Enzyme; Escherichia coli; Virology; Gene","routes":{"ca_aff":true,"ca_fund":true,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"codex-gemma-dda1882f352a","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0002069293,0.000314351,0.0002522004,0.0000199317,0.0007723895,0.00004498524,0.0004287525,0.0001274463,0.0004653863],"category_scores_gemma":[0.000003597514,0.0001673749,0.0001677381,0.00009856839,0.001283156,0.00006825035,0.0004977705,0.0003263561,0.0002099931],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.0001938198,"about_ca_system_score_gemma":0.000006284457,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.000443913,"about_ca_topic_score_gemma":0.0002784451,"domain_scores_codex":[0.9985188,0.0001620944,0.000342227,0.0004747809,0.000100885,0.0004012603],"domain_scores_gemma":[0.9988114,0.0002370788,0.0003036131,0.0005974406,0.00000161297,0.00004887281],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","study_design_scores_codex":[0.00007424007,0.0002169758,0.0008074007,0.000004278707,0.00002307573,0.000002294391,0.00008004278,0.00007076162,0.9964706,0.00006294787,0.001319774,0.0008675609],"study_design_scores_gemma":[0.0005402791,0.0001025862,0.05171309,0.000008536063,0.00005282647,0.00004001771,0.0002661135,0.000006834551,0.9002955,0.00009141403,0.04664506,0.00023772],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9934986,0.00008448665,0.00001699811,0.0006248895,0.0001715831,0.0005542176,0.0002514793,0.00001837254,0.004779413],"genre_scores_gemma":[0.9975591,0.00009930618,0.00003359563,0.0003540157,0.00005514371,0.00008154236,0.00003690706,0.00002598513,0.001754416],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.09617513,"threshold_uncertainty_score":0.6825349,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.001954402275879309,"score_gpt":0.1453802548217061,"score_spread":0.1434258525458268,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}